GCH1(GTP环化水解酶1, 磷酸鸟苷环 i, GTP-CH-I, DYT5, GCH)

产品简要

公司名称 :

US Biological

产品类型 :

抗体

产品名称 :

GCH1(GTP环化水解酶1, 磷酸鸟苷环 i, GTP-CH-I, DYT5, GCH)

G9005-98B

规格 :

100微克

价格 :

532美元

克隆性 :

多克隆

宿主 :

domestic goat

共轭标签 :

未共轭

反应物种 :

人类, 小鼠, 大鼠

更多信息或购买 :

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产品信息

目录号 :

G9005-98B

Product wo Prefix :

GCH1(GTP环化水解酶1, 磷酸鸟苷环 i, GTP-CH-I, DYT5, GCH)

宿主 :

山羊

产品类型 :

多克隆抗体

类别 :

抗体

尺寸1 :

100微克

Size1 List :

532美元

抗体亚型 :

IgG

Desc1 :

This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Western Blot: 0.5-1.5ug/ml, observed in human tonsil, lymph node and thymus lysates. on ~37kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo Rt

免疫原 :

Synthetic peptide corresponding to C-GKVHIGYLPNKQ, from human GCH1, at the internal region of the protein (NP_000152.1, NP_001019195.1).

特异性 :

Recognizes human GCH1. Species sequence homology: Mouse and rat.

纯度 :

经免疫亲和层析纯化

形式 :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

浓度 :

~0.5毫克/毫升

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-GKVHIGYLPNKQ, from human GCH1, at the internal region of the protein (NP_000152.1, NP_001019195.1). Specificity: Recognizes human GCH1. Species sequence homology: Mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E免疫印迹

储存温度 :

-20°C

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/47/G9005-98B_1.jpg

更多信息或购买 :

US Biological 产品网页

公司信息