产品简要
公司名称 :
US Biological
产品类型 :
抗体
产品名称 :
PAX5, ID (PAX5, Paired box protein Pax-5, B Cell-specific transcription factor)
目录 :
039702
规格 :
200微升
价格 :
569美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
039702
Product wo Prefix :
PAX5, ID (PAX5, Paired box protein Pax-5, B Cell-specific transcription factor)
宿主 :
兔
产品类型 :
多克隆抗体
类别 :
抗体
尺寸1 :
200微升
Size1 List :
569美元
抗体亚型 :
IgG
Desc1 :
This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.
Applications:
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA
Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50
Immunohistochemistry: 1:10-50
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
又名 :
PAX5, Paired box protein Pax-5, B-cell-specific transcription factor
免疫原 :
PAX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-215 amino acids from the Central region of human PAX5.
特异性 :
人类
纯度 :
Purified by Protein A affinity chromatography.
形式 :
以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠
浓度 :
As reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As reported
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity: Purified by Protein A affinity chromatography.
Immunogen: PAX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-215 amino acids from the Central region of human PAX5.
Specificity: Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E FC免疫组化免疫印迹
储存温度 :
-20°C
参考文献 :
Song, J., et al. Arch. Pathol. Lab. Med. 134(11):1702-1705(2010)
Okamoto, R., et al. Haematologica 95(9):1481-1488(2010)
Best, A., et al. Leuk. Res. 34(8):1098-1102(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Vidal, L.J., et al. Mol. Cancer Res. 8(3):444-456(2010)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/31/039702_1.jpg
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/12.png)
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
tech@usbio.net
https://www.usbio.net800-520-3011 781-639-5092
公司总部: 美国
United States Biological是生命科学领域的知名品牌,致力于用真实、有价值的个性化采购经验降低研究用成本。
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