抗体

MYH7, NT (MYH7, MYHCB, Myosin-7, Myosin heavy chain 7, Myosin heavy chain slow isoform, Myosin heavy chain, cardiac muscle beta isoform)

038729

200微升

569美元

多克隆

domestic rabbit

未共轭

MYH7, NT (MYH7, MYHCB, Myosin-7, Myosin heavy chain 7, Myosin heavy chain slow isoform, Myosin heavy chain, cardiac muscle beta isoform)

兔

多克隆抗体

抗体

200微升

569美元

IgG

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu Mo

MYH7, MYHCB, Myosin-7, Myosin heavy chain 7, Myosin heavy chain slow isoform, Myosin heavy chain, cardiac muscle beta isoform

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa184-211 in the N-terminal region of human MYH7, UniProt Accession #NP_000248.2; P12883

Recognizes human MYH7, NT. Species Crossreactivity: mouse.

经免疫亲和层析纯化

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by immunoaffinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa184-211 in the N-terminal region of human MYH7, UniProt Accession #NP_000248.2; P12883 Specificity: Recognizes human MYH7, NT. Species Crossreactivity: mouse. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

免疫印迹

-20°C

1. Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) : 2. Eijgelsheim, M., et al. Hum. Mol. Genet. 19(19):3885-3894(2010) 3. Millat, G., et al. Eur J Med Genet 53(5):261-267(2010) 4. Muelas, N., et al. Neurology 75(8):732-741(2010) 5. Zheng, D.D., et al. J. Int. Med. Res. 38(3):810-820(2010)

https://usbio-images.r.worldssl.net/prodimages/30/038729_1.jpg