抗体

HLA-DPA1, CT (HLA-DPA1, HLA-DP1A, HLASB, HLA class II histocompatibility antigen, DP alpha 1 chain, DP(W3), DP(W4), HLA-SB alpha chain, MHC class II DP3-alpha, MHC class II DPA1)

036620

200微升

569美元

多克隆

domestic rabbit

未共轭

HLA-DPA1, CT (HLA-DPA1, HLA-DP1A, HLASB, HLA class II histocompatibility antigen, DP alpha 1 chain, DP(W3), DP(W4), HLA-SB alpha chain, MHC class II DP3-alpha, MHC class II DPA1)

兔

多克隆抗体

抗体

200微升

569美元

IgG

HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

HLA-DPA1, HLA-DP1A, HLASB, HLA class II histocompatibility antigen, DP alpha 1 chain, DP(W3), DP(W4), HLA-SB alpha chain, MHC class II DP3-alpha, MHC class II DPA1

HLA-DPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the C-terminal region of human HLA-DPA1.

人类

Purified by Protein A affinity chromatography.

以溶解在PBS液体方式提供, pH值7.2, 0.09% 叠氮化钠

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: HLA-DPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the C-terminal region of human HLA-DPA1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

-20°C

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Varney, M.D., et al. Diabetes 59(8):2055-2062(2010) Ovsyannikova, I.G., et al. PLoS ONE 5 (7), E11806 (2010) : Mychaleckyj, J.C., et al. Clin Trials 7 (1 SUPPL), S75-S87 (2010) : Pacheco, P.R., et al. BMC Res Notes 3, 134 (2010) :

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