抗体

CLDN6, ID (CLDN6, Claudin-6, Skullin) (AP)

033967-AP

200微升

711美元

多克隆

domestic rabbit

AP

CLDN6, ID (CLDN6, Claudin-6, Skullin) (AP)

兔

多克隆抗体

AP

抗体

200微升

711美元

IgG

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu Mo

CLDN6, Claudin-6, Skullin

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 130-159 in the central region of human CLDN6, Swiss/UniProt Accession: P56747. Species sequence homology: Zebrafish

Recognizes human CLDN6. Species Crossreactivity: mouse

Purified by Protein A and peptide affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 130-159 in the central region of human CLDN6, Swiss/UniProt Accession: P56747. Species sequence homology: Zebrafish Specificity: Recognizes human CLDN6. Species Crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E免疫印迹

4°C不冻结

1. Wu, Q., et al. Eur. J. Cancer Prev. 19(3):186-194(2010) 2. Kleinschmidt-DeMasters, B.K., et al. Am. J. Surg. Pathol. 34(3):341-354(2010) 3. Rendon-Huerta, E., et al. J Gastrointest Cancer 41(1):52-59(2010) 4. Wu, Q., et al. Zhonghua Yi Xue Za Zhi 90(6):407-412(2010) 5. Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)

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