产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
Rhosin hydrochloride
目录 :
5003/10
规格 :
10 mg (also 50 mg)
价格 :
135美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 7
参考文献
Yamada S, Yassin M, Torelli F, Hansmann J, Green J, Schwarz T, et al. Unique osteogenic profile of bone marrow stem cells stimulated in perfusion bioreactor is Rho-ROCK-mediated contractility dependent. Bioeng Transl Med. 2023;8:e10509 pubmed 出版商
Ariyani W, Miyazaki W, Tsushima Y, Koibuchi N. Gadolinium-based contrast agent accelerates the migration of astrocyte via integrin αvβ3 signaling pathway. Sci Rep. 2022;12:5850 pubmed 出版商
Lim Y, Cho I, Rennke H, Cho G. β2-adrenergic receptor regulates ER-mitochondria contacts. Sci Rep. 2021;11:21477 pubmed 出版商
Malhi M, Norris M, Duan W, Moraes T, Maynes J. Statin-mediated disruption of Rho GTPase prenylation and activity inhibits respiratory syncytial virus infection. Commun Biol. 2021;4:1239 pubmed 出版商
Kim E, Jang J, Park J, Kim K, Yoon K, Yoo B, et al. Protein Arginine Methyltransferase 1 (PRMT1) Selective Inhibitor, TC-E 5003, Has Anti-Inflammatory Properties in TLR4 Signaling. Int J Mol Sci. 2020;21: pubmed 出版商
Mehra A, Guérit S, Macrez R, Gosselet F, Sevin E, Lebas H, et al. Nonionotropic Action of Endothelial NMDA Receptors on Blood-Brain Barrier Permeability via Rho/ROCK-Mediated Phosphorylation of Myosin. J Neurosci. 2020;40:1778-1787 pubmed 出版商
Zanin J, Verpeut J, Li Y, Shiflett M, Wang S, Santhakumar V, et al. The p75NTR Influences Cerebellar Circuit Development and Adult Behavior via Regulation of Cell Cycle Duration of Granule Cell Progenitors. J Neurosci. 2019;39:9119-9129 pubmed 出版商
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
5003
SKU号 :
5003/10
产品名称 :
Rhosin hydrochloride
描述 :
Rho inhibitor
靶标 :
Rho GTPase Inhibitors
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
98%
观察到的分子量 :
394.86
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Rhosin hydrochloride is a Rho GTPase inhibitor (Kd = 354 nM). Inhibits binding of RhoA to guanine nucleotide exchange factors (GEFs) including LARG, DBL, LBC, p115 RhoGEF and PDZ RhoGEF. Has no effect on the binding of Rac1 or Cdc42 to their respective GEFs. Suppresses RhoA/C-mediated breast cancer cell migration and invasion in vitro . Also induces neurite outgrowth in synergy with NGF.
extended description :
Rho inhibitor
化学品名文本 :
D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide hydrochloride
配方 :
C 20 H 18 N 6 O.氯化氢
配方文本 :
C20H18N6O.氯化氢
cas num :
1281870-42-5
美元 :
135美元
产品细节 :
Rho inhibitor
储存 :
存放在-20°C
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国