产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
SKF 83566 hydrobromide
目录 :
1586/10
规格 :
10 mg (also 50 mg)
价格 :
144美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 10
参考文献
Leng Z, Lin S, Wu Z, Guo Y, Cai L, Shang H, et al. Activation of DRD5 (dopamine receptor D5) inhibits tumor growth by autophagic cell death. Autophagy. 2017;13:1404-1419 pubmed 出版商
Li Y, Chen X, Dzakpasu R, Conant K. Dopamine-dependent effects on basal and glutamate stimulated network dynamics in cultured hippocampal neurons. J Neurochem. 2017;140:550-560 pubmed 出版商
Xing L, McDonald H, Da Fonte D, Gutierrez Villagomez J, Trudeau V. Dopamine D1 receptor activation regulates the expression of the estrogen synthesis gene aromatase B in radial glial cells. Front Neurosci. 2015;9:310 pubmed 出版商
Savalli G, Bashir Z, Warburton E. Regionally selective requirement for D1/D5 dopaminergic neurotransmission in the medial prefrontal cortex in object-in-place associative recognition memory. Learn Mem. 2015;22:69-73 pubmed 出版商
Cassar M, Issa A, Riemensperger T, Petitgas C, Rival T, Coulom H, et al. A dopamine receptor contributes to paraquat-induced neurotoxicity in Drosophila. Hum Mol Genet. 2015;24:197-212 pubmed 出版商
Huang Y, Levine A, Kandel D, Yin D, Colnaghi L, Drisaldi B, et al. D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus. Learn Mem. 2014;21:153-60 pubmed 出版商
Billes S, Simonds S, Cowley M. Leptin reduces food intake via a dopamine D2 receptor-dependent mechanism. Mol Metab. 2012;1:86-93 pubmed 出版商
Belinsky G, Sirois C, Rich M, Short S, Moore A, Gilbert S, et al. Dopamine receptors in human embryonic stem cell neurodifferentiation. Stem Cells Dev. 2013;22:1522-40 pubmed 出版商
Stramiello M, Wagner J. D1/5 receptor-mediated enhancement of LTP requires PKA, Src family kinases, and NR2B-containing NMDARs. Neuropharmacology. 2008;55:871-7 pubmed 出版商
Liu T, Dartevelle L, Yuan C, Wei H, Wang Y, Ferveur J, et al. Increased dopamine level enhances male-male courtship in Drosophila. J Neurosci. 2008;28:5539-46 pubmed 出版商
产品信息
品牌 :
Tocris
MasterCode :
1586
SKU号 :
1586/10
产品名称 :
SKF 83566 hydrobromide
靶标 :
Dopamine D1 and D5 Receptor Antagonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
98%
观察到的分子量 :
413.15
网址印刷 :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
SKF 83566 hydrobromide is a potent and selective D1-like dopamine receptor antagonist (Ki~ 0.56 nM for D1; KB = 2 u M for D2). Also antagonist at the vascular 5-HT2 receptor (Ki = 11 nM). Displays selective inhibition of adenylyl cyclase 2 (AC2); inactive against AC1 or AC5. Centrally active following systemic administration in vivo .
extended description :
Potent and selective D1-like antagonist; also inhibits adenylyl cyclase 2
化学品名文本 :
8-Bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrobromide
配方 :
C 17 H 18 BrNO.HBr
配方文本 :
C17H18BrNO.HBr
cas num :
108179-91-5
美元 :
144美元
产品细节 :
Potent and selective D1-like antagonist; also inhibits adenylyl cyclase 2
储存 :
Desiccate at RT
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国