产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
Tertiapin-Q
目录 :
1316/1
规格 :
1毫克
价格 :
539美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 10
参考文献
Patel D, Kuyucak S, Doupnik C. Structural Determinants Mediating Tertiapin Block of Neuronal Kir3.2 Channels. Biochemistry. 2020;59:836-850 pubmed 出版商
Aguilar Sanchez Y, Rodríguez de Yurre A, Argenziano M, Escobar A, Ramos Franco J. Transmural Autonomic Regulation of Cardiac Contractility at the Intact Heart Level. Front Physiol. 2019;10:773 pubmed 出版商
Llamosas N, Ugedo L, Torrecilla M. Inactivation of GIRK channels weakens the pre- and postsynaptic inhibitory activity in dorsal raphe neurons. Physiol Rep. 2017;5: pubmed 出版商
Workman E, Haddick P, Bush K, Dilly G, Niere F, Zemelman B, et al. Rapid antidepressants stimulate the decoupling of GABA(B) receptors from GIRK/Kir3 channels through increased protein stability of 14-3-3η. Mol Psychiatry. 2015;20:298-310 pubmed 出版商
Stott J, Barrese V, Jepps T, Leighton E, Greenwood I. Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats. Hypertension. 2015;65:676-82 pubmed 出版商
Marcott P, Mamaligas A, Ford C. Phasic dopamine release drives rapid activation of striatal D2-receptors. Neuron. 2014;84:164-176 pubmed 出版商
Chu C, Jin W, Bing Y, Jin Q, Kannan H, Qiu D. Effects of stresscopin on rat hypothalamic paraventricular nucleus neurons in vitro. PLoS ONE. 2013;8:e53863 pubmed 出版商
Choisy S, James A, Hancox J. Acute desensitization of acetylcholine and endothelin-1 activated inward rectifier K+ current in myocytes from the cardiac atrioventricular node. Biochem Biophys Res Commun. 2012;423:496-502 pubmed 出版商
Choisy S, Cheng H, Smith G, James A, Hancox J. Modulation by endothelin-1 of spontaneous activity and membrane currents of atrioventricular node myocytes from the rabbit heart. PLoS ONE. 2012;7:e33448 pubmed 出版商
Yi Y, Sung D, Millette C, Sutovsky M, Kennedy C, Sutovsky P, et al. Sperm GIRK2-containing K+ inward rectifying channels participate in sperm capacitation and fertilization. Syst Biol Reprod Med. 2011;57:296-308 pubmed 出版商
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1316
SKU号 :
1316/1
产品名称 :
Tertiapin-Q
描述 :
Selective blocker of inward-rectifier K+ channels
靶标 :
Inward Rectifier Potassium Channel Blockers
类别 :
肽
单位尺寸 :
1毫克
纯度 :
95%
观察到的分子量 :
2452
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides
功能细节 :
Tertiapin-Q is a high affinity blocker for inward-rectifier K+ channels. Tertiapin-Q is a stable derivative of the bee venom toxin tertiapin. Tertiapin-Q binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with high affinity (Ki values are 1.3 and 13.3 nM respectively) and is selective over Kir2.1 channels. Tertiapin-Q improves heart rate and atrioventricular conduction in a mouse model of bradycardia. Derivative Tertiapin LQ (Cat. No. 4339) also available.
extended description :
Selective blocker of inward-rectifier K+ channels
配方 :
C 106 H 175 N 35 O 24秒4
配方文本 :
C106H175N35O24S4
cas num :
910044-56-3
美元 :
539美元
产品细节 :
Selective blocker of inward-rectifier K+ channels
储存 :
存放在-20°C
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国