产品简要
公司名称 :
Rockland Immunochemicals
产品类型 :
抗体
产品名称 :
p53磷酸化S392抗体
目录 :
600-401-E04
规格 :
100微升
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹
更多信息或购买 :
产品信息
目录号 :
600-401-E04
名称 :
抗p53 pS392(兔)抗体-600-401
显示名称 :
p53磷酸化S392抗体
应用注释 :
Anti-p53 pS392 Antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 53 kDa in size corresponding to p53 protein phosphorylated at Ser392 in the appropriate cell lysate or extract.
缓冲液 :
0.01 M羟乙基哌嗪乙磺酸, 0.15 M氯化钠, pH值7.5
克隆性 :
多克隆
浓度值 :
Titrated value sufficient to run approximately 10 mini blots.
共轭 :
(None)
规格 :
100微升
默认单元 :
微升
免疫印迹稀释浓度 :
1:1000
有效期 :
Expiration date is one (1) year from date of opening.
格式 :
IgG
基因名称 :
TP53
宿主动物 :
兔
一般免责声明 :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
免疫原 :
Anti-p53 pS392 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser392.
包装类型 :
干冰
物理状态 :
液体
纯度和特异性 :
Anti-p53 pS392 antibody is directed against p53 phosphorylated at S392. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. The immunolabeling is completely eliminated by lambda-phosphatase treatment. Reactivity is expected the following species based on 100% sequence homology: human and rat. Cross reactivity with p53 from other species has not been determined
物种活性 :
大鼠
稳定剂 :
0.1毫克/毫升牛血清白蛋白(BSA)-不含IgG和蛋白酶, 50%(v/v)甘油
储存 :
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
同义词 :
Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
靶物种 :
人类
背景 :
p53 pS392 Antibody detects phophorylated p53. p53 has a well established role in blocking the proliferative action of damaged cells and acting in essence as an anticancer agent. It has been called the guardian of the genome. Phosphorylation of Ser392 in p53 is associated with formation of human tumors. In addition, p53 has been linked to effects of aging and oxidative stress. An increase in p53 has also been linked to deficits in LTP and learning and memory. Anti-p53 pS392 Antibody is ideal for investigators involved in Transcription Factor, Cell Cycle, Apoptosis, and Cancer research.
免疫原类型 :
多肽
低内毒素 :
No
翻译后的修饰作用 :
磷酸化
样品尺寸 :
No
靶活性结构域 :
内部
应用文本 :
免疫印迹
其他 :
User Optimized
类别 :
一抗
共轭名称 :
未共轭
UniProt数据库 :
P04637
NCBI :
BAC16799.1
最初图像名称 :
Western blot of Anti-p53 pS392 (Rabbit) Antibody - 600-401-E04
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/37.png)
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
Pottstown, PA 19464
orders@rockland-inc.com
https://www.rockland.com/800-656-7625
公司总部: 美国
Rockland Immunochemicals, Inc.位于宾夕法尼亚州的费城西部,为基础研究、应用研究及临床研究提供磷酸化位点特异性抗体及抗体相关研究工具。公司的技术平台是由一批经验丰富的科学家建立,利用In vitro及In vivo方法制备并纯化单抗及多抗,这些抗体应用于免疫印迹、ELISA、免疫组化、荧光检测、高通量筛选及诊断试剂盒生产等。常用一抗主要应用于以下研究:Akt通路、载脂蛋白、细胞凋亡/细胞周期、细胞因子、细胞信号、酶类、胞外基质、转录因子及泛素相关领域。