抗体

NF2磷酸化S518抗体

600-401-414

100微克

369.00美元

多克隆

domestic rabbit

未共轭

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化

抗NF2(默林)pS518(兔)抗体-600-401

NF2磷酸化S518抗体

This phospho-specific polyclonal antibody was tested by immunoblotting and ELISA.  By ELISA, the antibody was found to be reactive with the phosphorylated form of the immunizing peptide and minimally reactive with the non-phosphorylated form of the immunizing peptide.   Immunoblotting will detect human and mouse NF2 (Merlin).  Although not tested, this antibody is likely functional in immunohistochemistry and immunoprecipitation.

0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2

多克隆

1.0毫克/毫升

by UV absorbance at 280 nm

(None)

100微克

微克

1:1,200,000

User Optimized

1:500- 1:2, 000

Expiration date is one (1) year from date of opening.

IgG

NF2

兔

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Human NF2 (Merlin) phospho-peptide corresponding to a region of the human protein surrounding S518 and conjugated to Keyhole Limpet Hemocyanin (KLH).

干冰

Liquid (sterile filtered)

0.01%(w/v)叠氮化钠

This affinity purified antibody is directed against human NF2 (Neurofibromatosis 2 gene product).  The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.  Antiserum was first purified against the phosphorylated form of the immunizing peptide.  The resultant affinity purified antibody was then cross-adsorbed against the non-phosphorylated form of the immunizing peptide.  This phospho-specific polyclonal antibody is specific for phosphorylated pS518 of human NF2 (neurofibromatosis 2 gene product).   Reactivity with non-phosphorylated Human NF2 (Merlin) is minimal by ELISA.   Cross-reactivity with NF2 (Merlin) occurs in mouse tissue.  Reactivity with NF2 from other sources has not been determined.

小鼠

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

rabbit anti-NF2 pS518 antibody, rabbit anti-Merlin pS518 antibody, moesin ezrin radixin like protein antibody, Neurofibromatosis 2 antibody, Neurofibromin-2, Schwannomerlin, Schwannomin, Merlin, NF 2, NF-2, SCH

人类

The recently isolated neurofibromatosis 2 tumor suppressor gene encodes a 595 amino acid protein (Merlin).  The protein product Merlin, named for its relatedness to the ezrin, radixin and moesin (ERM) family of proteins, is a tumor suppressor whose absence results in the occurrence of multiple tumors of the nervous system, particularly schwannomas and meningiomas. Merlin's similarity to ERM’s suggests that it might share functions, acting as a link between cytoskeletal components and the cell membrane.  The NF2 protein is highly expressed in human fibroblasts and is detected as a single band of about 75kDa.  This antibody is specific for the phosphorylated form of human NF2 (Merlin).

多肽

No

磷酸化

No

酶联免疫吸附测定, 免疫组化, 免疫印迹

User Optimized

一抗

未共轭

369.00美元

P35240

NP_000259

抗人类NF2(默林)pS518抗体-免疫印迹