抗体

ZBP-89抗体

100-401-685

100微升

多克隆

domestic rabbit

未共轭

免疫印迹, 酶联免疫吸附测定

抗ZBP-89(兔)抗体-100-401

ZBP-89抗体

This polyclonal antibody reacts human ZBP-89 in a variety of immunological assays including western blot and ELISA.  Although not tested, this antibody is likely functional in immunohistochemistry and immunoprecipitation. For immunoblotting a 1:5,000 dilution is recommended. A band at approximately 89 kDa corresponding to human ZBP-89 is detected. Human monocytes or macrophages or nuclear extracts from PMA treated U937 cells can be used as a positive control. For ELISA a 1:10,000 to 1:30,000 dilution is recommended. Researchers should determine optimal titers for other applications.

多克隆

90毫克/毫升

by Refractometry

(None)

100微升

微升

1:10, 000 - 1:30, 000

1:5,000

Expiration date is one (1) year from date of opening.

抗血清

ZNF148

兔

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

纯化全长ZBP-89重组蛋白在大肠杆菌中表达

干冰

Liquid (sterile filtered)

0.1%(w/v)叠氮化钠

Anti-ZBP89 antibody was prepared from monospecific antiserum by delipidation and defibrination. This polyclonal antibody is specific for human ZBP-89.  Reactivity with ZBP-89 from other species has not been determined.

人类

Store ZBP89 Antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

兔抗ZBP-89抗体, 转录因子ZBP89抗体, 锌指DNA结合蛋白89抗体, 锌指蛋白148抗体, ZNF 148抗体, 锌指蛋白148, 转录因子ZBP-89, ZNF148

人类

The GI tract abundantly expresses growth factors many of which bind and activate the EGF receptor present on mucosal cells. One such factor is the zinc finger protein (ZBP-89) that binds to a GC-rich DNA element in the gastrin promoter and confers EGF responsiveness. The full-length protein functions as a repressor of growth factor signals regulating the gastrin promoter. Several other growth related promoters are also regulated by ZBP-89. ZBP-89 is one of a family of related transcriptional regulators. It has been reported in recent studies that ZBP-89 regulates growth in part by stimulating the cyclin-dependent kinase inhibitor, p21waf1, in a butyrate-dependent manner through recruitment of the histone acetyl transferase p300. Moreover, ZBP-89 triggers growth arrest in a p53-dependent manner by preventing nuclear export of p53. ZBP-89 also induces apoptosis, but this process occurs independent of p53.

重组蛋白

No

No

酶联免疫吸附测定, 免疫印迹

User Optimized

一抗

未共轭

Q9UQR1

CAA15422.1

抗ZBP-89抗体-免疫印迹