产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组小鼠丝氨酸蛋白酶抑制剂A3N蛋白, CF
目录 :
4709-主要研究者
规格 :
10微克
价格 :
447美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 4
参考文献
Kim H, Leng K, Park J, Sorets A, Kim S, Shostak A, et al. Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin. Nat Commun. 2022;13:6581 pubmed 出版商
Ho Y, Shimbo T, Wijaya E, Kitayama T, Takaki S, Ikegami K, et al. Longitudinal Single-Cell Transcriptomics Reveals a Role for Serpina3n-Mediated Resolution of Inflammation in a Mouse Colitis Model. Cell Mol Gastroenterol Hepatol. 2021;12:547-566 pubmed 出版商
Zhang H, Wang P, Li Y, Bao Y. SerpinA3n affects ovalbumin (OVA)-induced asthma in neonatal mice via the regulation of collagen deposition and inflammatory response. Respir Physiol Neurobiol. 2021;288:103642 pubmed 出版商
Vicuña L, Strochlic D, Latremoliere A, Bali K, Simonetti M, Husainie D, et al. The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase. Nat Med. 2015;21:518-23 pubmed 出版商
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
4709-主要研究者
SKU号 :
4709-主要研究者
产品名称 :
重组小鼠丝氨酸蛋白酶抑制剂A3N蛋白, CF
描述 :
The Recombinant Mouse Serpin A3N Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Serpin A3N Protein, CF has been validated for the following applications: Inhibition Activity.
靶标 :
丝氨酸蛋白酶抑制剂A3N
类别 :
蛋白和酶
单位尺寸 :
10微克
缓冲液 :
Supplied as a 0.2 µm filtered solution in Tris and NaCl.
共轭标签 :
未共轭
纯度 :
>85%, by SDS-PAGE under reducing conditions and visualized by silver stain.
物种 :
小鼠
观察到的分子量 :
59 kDa, reducing conditions
理论上的分子量 :
46 kDa
基因符号 :
Serpina3n
功能细节 :
Measured by its ability to inhibit Granzyme B cleavage of tert -butoxycarbonyl-Ala-Ala-Asp-thiobenzyl ester (Boc-AAD-SBzl). The IC50 is 25 nM, as measured under the described conditions.
内毒素说明 :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q91WP6
应用 :
抑制作用活性
来源 :
NS0-derived Recombinant Mouse Serpin A3N Protein
美元 :
447美元
别名 :
A1A;A1AT;AAT;甲1;alpha1AT;nNIF;主要研究者;PI1;PRO2275;SERPINA1, Spi2
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.