重组人类HGFR/c-met原癌基因Fc嵌合体多聚组氨酸标签蛋白, CF

产品简要

公司名称 :

安迪生物R&D

产品类型 :

蛋白

产品名称 :

重组人类HGFR/c-met原癌基因Fc嵌合体多聚组氨酸标签蛋白, CF

358-MT-100/CF

规格 :

100微克

价格 :

447美元

更多信息或购买 :

安迪生物R&D 产品网页

文章摘录数: 6

参考文献
Miao W, Sakai K, Ozawa N, Nishiuchi T, Suzuki Y, Ito K, et al. Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist. Sci Rep. 2018;8:16492 pubmed 出版商
Kaye D, Pinto P, Cecchi F, Reilly J, Semerjian A, Rabe D, et al. Tumor and Plasma Met Levels in Non-Metastatic Prostate Cancer. PLoS ONE. 2016;11:e0157130 pubmed 出版商
Moores S, Chiu M, Bushey B, Chevalier K, Luistro L, Dorn K, et al. A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors. Cancer Res. 2016;76:3942-53 pubmed 出版商
Liu L, Zeng W, Wortinger M, Yan S, Cornwell P, Peek V, et al. LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth. Clin Cancer Res. 2014;20:6059-70 pubmed 出版商
Tabernero J, Elez M, Herranz M, Rico I, Prudkin L, Andreu J, et al. A pharmacodynamic/pharmacokinetic study of ficlatuzumab in patients with advanced solid tumors and liver metastases. Clin Cancer Res. 2014;20:2793-804 pubmed 出版商
Boltz A, Piater B, Toleikis L, Guenther R, Kolmar H, Hock B. Bi-specific aptamers mediating tumor cell lysis. J Biol Chem. 2011;286:21896-905 pubmed 出版商

产品信息

品牌 :

R&D Systems, a Bio-Techne Brand

catalog number base :

358-MT/CF

SKU号 :

358-MT-100/CF

产品名称 :

重组人类HGFR/c-met原癌基因Fc嵌合体多聚组氨酸标签蛋白, CF

描述 :

The Recombinant Human HGFR/c-MET Fc Chimera His-tag Protein, CF from R&D Systems is derived from NS0. The Recombinant Human HGFR/c-MET Fc Chimera His-tag Protein, CF has been validated for the following applications: Binding Activity.

靶标 :

HGFR/c-met原癌基因

类别 :

蛋白和酶

单位尺寸 :

100微克

缓冲液 :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose.

共轭标签 :

未共轭

纯度 :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

物种 :

人类

观察到的分子量 :

43-50 kDa (alpha chain) and 120-125 kDa (beta chain)

理论上的分子量 :

32.5 kDa (alpha chain), 96.7 kDa (beta chain)

基因符号 :

met原癌基因

功能细节 :

Measured by its ability to bind rhHGF in a functional ELISA with an estimated Kd 0.5 nM.

内毒素说明 :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P08581

应用 :

结合活性

来源 :

NS0-derived Recombinant Human HGFR/c-MET Fc Chimera His-tag Protein

美元 :

447美元

别名 :

AUTS9, c met原癌基因, cMET, EC 2.7。 10, EC 2.7。 10.1, 肝细胞生长因子受体, HGF R, 肝细胞生长因子受体, HGF/SF受体, HGFR, met原癌基因, met原癌基因(c met原癌基因), met原癌基因原癌基因(肝细胞生长因子受体), met原癌基因原癌基因酪氨酸激酶, 癌基因met原癌基因, 原癌基因c met原癌基因, RCCP2, 分散因子受体, SF受体, 酪氨酸蛋白激酶met原癌基因

储存 :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

更多信息或购买 :

安迪生物R&D 产品网页

公司信息

安迪生物R&D

上海市长宁区延安西路726号华敏翰尊国际大厦24A1

info@rndsystemschina.com.cn

http://www.rndsystemschina.com.cn

21 52380373

公司总部: 美国

R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.