产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类MSP/MST1蛋白, CF
目录 :
352-MS-010/CF
规格 :
10 ug (also 50 ug)
价格 :
365美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 8
参考文献
Khaibullina A, Adjei E, Afangbedji N, Ivanov A, Kumari N, Almeida L, et al. RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice. Haematologica. 2018;103:787-798 pubmed 出版商
Yin B, Liu Z, Wang Y, Wang X, Liu W, Yu P, et al. RON and c-Met facilitate metastasis through the ERK signaling pathway in prostate cancer cells. Oncol Rep. 2017;37:3209-3218 pubmed 出版商
Vladimer G, Snijder B, Krall N, Bigenzahn J, Huber K, Lardeau C, et al. Global survey of the immunomodulatory potential of common drugs. Nat Chem Biol. 2017;13:681-690 pubmed 出版商
Zhou D, Li C, Yang L. Variant RONΔ160 of the RON receptor tyrosine kinase promotes the growth and invasion in vitro and in vivo in gastric cancer cell lines. Cancer Cell Int. 2015;15:9 pubmed 出版商
Yang C, Kim J, Kim T, Lee P, Kim S, Lee H, et al. Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome. Nat Commun. 2015;6:6115 pubmed 出版商
Bhatt A, Welm A, Farady C, Vasquez M, Wilson K, Craik C. Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway. Proc Natl Acad Sci U S A. 2007;104:5771-6 pubmed
Gunella G, Bardelli C, Amoruso A, Viano I, Balbo P, Brunelleschi S. Macrophage-stimulating protein differently affects human alveolar macrophages from smoker and non-smoker patients: evaluation of respiratory burst, cytokine release and NF-kappaB pathway. Br J Pharmacol. 2006;148:478-89 pubmed
Rampino T, Collesi C, Gregorini M, Maggio M, Soccio G, Guallini P, et al. Macrophage-stimulating protein is produced by tubular cells and activates mesangial cells. J Am Soc Nephrol. 2002;13:649-57 pubmed
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
352-MS/CF
SKU号 :
352-MS-010/CF
产品名称 :
重组人类MSP/MST1蛋白, CF
描述 :
The Recombinant Human MSP/MST1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human MSP/MST1 Protein, CF has been validated for the following applications: Bioactivity.
靶标 :
MSP/MST1
类别 :
蛋白和酶
单位尺寸 :
10 ug (also 50 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS.
共轭标签 :
未共轭
纯度 :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
物种 :
人类
观察到的分子量 :
81 kDa, 62 kDa and 30 kDa, reducing conditions
理论上的分子量 :
78.5 kDa (MSP alpha/beta ); 53.3 kDa ( alpha chain), 25.2 kDa ( beta chain)
基因符号 :
MST1
功能细节 :
Measured by its ability to activate MSP R/Ron in MDA-MB-453 or T47D human breast cancer cells. 80 ng/mL of the recombinant human MSP significantly induces phosphorylation of MSP R/Ron measured by the Human Phospho-MSP R/Ron DuoSet® IC Kit (Catalog # DYC1947 ). Measured by its binding ability in a functional ELISA. When Recombinant Human MSPR/Ron Protein (Catalog #1947-MS) is represent at 100 ng/mL (100 µg/mL), The concentration of Recombinant Human MSP/MST1 that produces 50% optimal binding response is found to be 8-40 ng/mL.
内毒素说明 :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAA59872
应用 :
Bioactivity
来源 :
NS0-derived Recombinant Human MSP/MST1 Protein
美元 :
365美元
别名 :
D3F15S2, EC 3.4.21, hepatocyte growth factor-like protein homolog, HGFL, HGFLhepatocyte growth factor-like protein, macrophage stimulating 1 (hepatocyte growth factor-like), Macrophage stimulatory protein, Macrophage-stimulating protein, MSPDNF15S2, MST1, NF15S2, SF2
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.