产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类TREM-1 Fc嵌合体蛋白, CF
目录 :
1278-TR-050
规格 :
50微克
价格 :
423美元
更多信息或购买 :
文章摘录数: 3
参考文献
Sudom A, Talreja S, Danao J, Bragg E, Kegel R, Min X, et al. Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2. J Biol Chem. 2018;293:12634-12646 pubmed 出版商
Zhao Y, Wu X, Li X, Jiang L, Gui X, Liu Y, et al. TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function. Neuron. 2018;97:1023-1031.e7 pubmed 出版商
Horonenko G, Hoyt J, Robbins R, Singarajah C, Umar A, Pattengill J, et al. Soluble triggering receptor expressed on myeloid cell-1 is increased in patients with ventilator-associated pneumonia: a preliminary report. Chest. 2007;132:58-63 pubmed
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
1278-TR
SKU号 :
1278-TR-050
产品名称 :
重组人类TREM-1 Fc嵌合体蛋白, CF
描述 :
The Recombinant Human TREM-1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human TREM-1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
靶标 :
TREM-1
类别 :
蛋白和酶
单位尺寸 :
50微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS.
共轭标签 :
未共轭
纯度 :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
物种 :
人类
观察到的分子量 :
60-70 kDa, reducing conditions
理论上的分子量 :
47 kDa (monomer)
基因符号 :
TREM1
功能细节 :
Measured by its ability to block anti-TREM-1-induced TNF-alpha secretion by human peripheral blood mononuclear cells (PBMC). At 1 µg/mL, Recombinant Human TREM-1 Fc Chimera is able to block 70% of Goat Anti-Human TREM-1 (20 µg/mL, 200 µL/well) (Catalog # AF1278) induced TNF-alpha released from 1 x 105 cells.
内毒素说明 :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q9NP99
应用 :
Bioactivity
来源 :
NS0-derived Recombinant Human TREM-1 Fc Chimera Protein
美元 :
423美元
别名 :
CD354, CD354 antigen, TREM1, TREM-1Triggering receptor expressed on monocytes 1, triggering receptor expressed on myeloid cells 1, triggering-receptor TREM1
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.