抗体

抗脑源性神经营养因子(BDNF)抗体

50170-500

500微克

432美元

单克隆

小鼠

未共轭

蚂蚁-128

抗脑源性神经营养因子(BDNF)抗体

抗脑源性神经营养因子(BDNF)抗体(50170-500)

抗体

抗人类脑源性神经营养因子小鼠单克隆抗体

人类脑源性神经营养因子

人类

脑源性神经营养因子(BDNF)

P23560

Secreted

脑源性神经营养因子

BDNF

单克隆

冻干

1.0毫克/毫升

500微克

432美元

302.4

50170-500

酶联免疫吸附测定

ELISA: use at 0.1-1ug/ml with BDNF on the solid phase. These are recommended concentrations. Endusers should determine optimal concentrations for their applications.

小鼠

纯化

IgG

蚂蚁-128

重组人类BDNF

生长因子, 细胞因子, 受体

Lyophilized at 1mg/ml in PBS.

磷酸盐缓冲液

Important signaling molecule that activates signaling cascades downstream of NTRK2 (PubMed:11152678). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. {PubMed:11152678, PubMed:12553913, PubMed:29909994}.; [BDNF precursor form]: Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2 (PubMed:24908487, PubMed:29909994). Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse (By similarity). {UniProtKB:P21237, PubMed:24908487, PubMed:29909994}.

This antibody is stable for 1 month at 4°C or one year at -20°C. Avoid multiple freeze-thaw cycles.