产品简要
公司名称 :
QED Bioscience
产品类型 :
抗体
产品名称 :
抗STAT5A(磷酸化Tyr694)抗体
目录 :
43048
规格 :
100微升
价格 :
345美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
更多信息或购买 :
QED Bioscience 产品网页
产品信息
目录号 :
43048
产品名称 :
抗STAT5A(磷酸化Tyr694)抗体
NAME+SKU :
抗STAT5A(磷酸化Tyr694)抗体(43048)
产品_TYPE :
抗体
描述 :
抗STAT5A(磷酸化Tyr694)兔多克隆抗体
SPECIFICITY SHORT :
STAT5A(磷酸化Tyr694)
物种活性 :
人类, 小鼠, 大鼠
靶标名 :
STAT5A(磷酸化Tyr694)
靶抗原修饰 :
磷酸化tyr694
UniProt数据库 :
P42229
LOCATION :
Cytoplasm , Nucleus
蛋白名 :
Signal transducer and activator of transcription 5A
基因名称 :
STAT5A
克隆性 :
多克隆
形式 :
液体
浓度 :
1.0毫克/毫升
规格1 :
100微升
标价规格1 :
345美元
DISTIRBUTOR价格 :
241.5
SKU号规格1 :
43048
应用 :
免疫印迹, 免疫组化
应用INSTRUCTIONS :
Immunoblotting: use at dilution of 1:500-1:1,000. A band of~90kDa is detected. Immunohistochemistry: use at dilution of 1:50- 1:100. These are recommended working dilutions. Enduser should determine optimal dilutions for their applications.
宿主 :
兔
格式 :
纯化
纯化 :
经免疫亲和层析纯化
免疫原 :
Peptide sequence that includes phosphorylation site of tyrosine 694 (D-G-Y(p)-V-K) derived from human STAT5A and conjugated to KLH.
研究领域 :
磷酸化特异性抗体
配方 :
PBS (without Mg2 and Ca2 ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
缓冲液 :
磷酸盐缓冲液
缓冲液pH值 :
pH值7.4
缓冲液抗MICROBIAL :
0.02% 叠氮化钠
缓冲液CRYOPRESERVATIVE :
50% 甘油
靶标背景 :
Signal transducers and activators of transcription (STATs) are transcription factors that play important roles in signaling pathways induced by many different cytokines and growth factors that regulate cell growth and differentiation, the immune response, antiviral activity, and homeostasis. Their activation and mechanisms of action are examples of direct signaling to the nucleus by extracellular polypeptide ligands without the involvement of second messengers, tyrosine phosphorylation of transcription factors, or transcription factors that make direct contact with membrane-bound receptors and DNA. Since the discovery of STAT 1 and 2, the family has been expanded to seven members.
FUNCTION :
Carries out a dual signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation. {PubMed:15534001}.
稀释INSTRUCTIONS :
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE空调 :
This antibody is stable for at least one (1) year at -20C. Can be stored at 4C for short-term use.
特异性 :
This antibody detects endogenous human, mouse, and rat STAT5A only when phosphorylated at tyrosine 694.
更多信息或购买 :
QED Bioscience 产品网页
公司信息
QED Bioscience
10919 Technology Place, Suite C San Diego, CA 92127
info@qedbio.com
http://www.qedbio.com
800-929-2114 858-675-2405
公司总部: 美国