产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
A20/TNFAIP3 Antibody (59A426) - BSA Free
目录 :
NBP1-77533
规格 :
0.1 mg (also 0.025 mg)
价格 :
469美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
59A426
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 42
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Reihill J, Malcomson B, Bertelsen A, Cheung S, Czerwiec A, Barsden R, et al. Induction of the inflammatory regulator A20 by gibberellic acid in airway epithelial cells. Br J Pharmacol. 2016;173:778-89 pubmed 出版商
  • 免疫印迹; 小鼠
Perez C, Jukica A, Listopad J, Anders K, Kühl A, Loddenkemper C, et al. Permissive expansion and homing of adoptively transferred T cells in tumor-bearing hosts. Int J Cancer. 2015;137:359-71 pubmed 出版商
  • 免疫印迹; 小鼠
De A, Dainichi T, RATHINAM C, Ghosh S. The deubiquitinase activity of A20 is dispensable for NF-?B signaling. EMBO Rep. 2014;15:775-83 pubmed 出版商
Wang Y, Liu T, Shen C, Lin S, Hung C, Hsu L, et al. K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy. Cell Rep. 2022;38:110354 pubmed 出版商
Tran V, Ju H. Fluorescence Based on Surface Plasmon Coupled Emission for Ultrahigh Sensitivity Immunoassay of Cardiac Troponin I. Biomedicines. 2021;9: pubmed 出版商
Feoktistova M, Makarov R, Brenji S, Schneider A, Hooiveld G, Luedde T, et al. A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes. Cells. 2020;9: pubmed 出版商
Ma J, Xiao Y, Tian B, Chen S, Zhang B, Wu J, et al. Genome-wide analyses of long non-coding RNA expression profiles and functional network analysis in esophageal squamous cell carcinoma. Sci Rep. 2019;9:9162 pubmed 出版商
Lim M, Maubach G, Sokolova O, Feige M, Diezko R, Buchbinder J, et al. Pathogen-induced ubiquitin-editing enzyme A20 bifunctionally shuts off NF-κB and caspase-8-dependent apoptotic cell death. Cell Death Differ. 2017;24:1621-1631 pubmed 出版商
Lai T, Wu S, Tsai M, Chuang E, Chuang L, Hsu L, et al. Transcription of Tnfaip3 is regulated by NF-?B and p38 via C/EBP? in activated macrophages. PLoS ONE. 2013;8:e73153 pubmed 出版商
Svingerud T, Solstad T, Sun B, Nyrud M, Kileng y, Greiner Tollersrud L, et al. Atlantic salmon type I IFN subtypes show differences in antiviral activity and cell-dependent expression: evidence for high IFNb/IFNc-producing cells in fish lymphoid tissues. J Immunol. 2012;189:5912-23 pubmed 出版商
Karube K, Nakagawa M, Tsuzuki S, Takeuchi I, Honma K, Nakashima Y, et al. Identification of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell neoplasms by genomic and functional analyses. Blood. 2011;118:3195-204 pubmed 出版商
Gerlach B, Cordier S, Schmukle A, Emmerich C, Rieser E, Haas T, et al. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature. 2011;471:591-6 pubmed 出版商
Hövelmeyer N, Reissig S, Xuan N, Adams Quack P, Lukas D, Nikolaev A, et al. A20 deficiency in B cells enhances B-cell proliferation and results in the development of autoantibodies. Eur J Immunol. 2011;41:595-601 pubmed 出版商
Adrianto I, Wen F, Templeton A, Wiley G, King J, Lessard C, et al. Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. Nat Genet. 2011;43:253-8 pubmed 出版商
Imbeault M, Ouellet M, Giguère K, Bertin J, Bélanger D, Martin G, et al. Acquisition of host-derived CD40L by HIV-1 in vivo and its functional consequences in the B-cell compartment. J Virol. 2011;85:2189-200 pubmed 出版商
Malinverni C, Unterreiner A, Staal J, Demeyer A, Galaup M, Luyten M, et al. Cleavage by MALT1 induces cytosolic release of A20. Biochem Biophys Res Commun. 2010;400:543-7 pubmed 出版商
Frenzel L, Claus R, Plume N, Schwamb J, Konermann C, Pallasch C, et al. Sustained NF-kappaB activity in chronic lymphocytic leukemia is independent of genetic and epigenetic alterations in the TNFAIP3 (A20) locus. Int J Cancer. 2011;128:2495-500 pubmed 出版商
Harada Y, Kanehira M, Fujisawa Y, Takata R, Shuin T, Miki T, et al. Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells. Cancer Res. 2010;70:5829-39 pubmed 出版商
Hjelmeland A, Wu Q, Wickman S, Eyler C, Heddleston J, Shi Q, et al. Targeting A20 decreases glioma stem cell survival and tumor growth. PLoS Biol. 2010;8:e1000319 pubmed 出版商
Hailfinger S, Lenz G, Ngo V, Posvitz Fejfar A, Rebeaud F, Guzzardi M, et al. Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A. 2009;106:19946-51 pubmed 出版商
Metellus P, Coulibaly B, Nanni I, Fina F, Eudes N, Giorgi R, et al. Prognostic impact of O6-methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation: a prospective patient cohort. Cancer. 2009;115:4783-94 pubmed 出版商
Honma K, Tsuzuki S, Nakagawa M, Tagawa H, Nakamura S, Morishima Y, et al. TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas. Blood. 2009;114:2467-75 pubmed 出版商
Duwel M, Welteke V, Oeckinghaus A, Baens M, Kloo B, Ferch U, et al. A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains. J Immunol. 2009;182:7718-28 pubmed 出版商
Schmitz R, Hansmann M, Bohle V, Martin Subero J, Hartmann S, Mechtersheimer G, et al. TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma. J Exp Med. 2009;206:981-9 pubmed 出版商
Verhelst K, Verstrepen L, Coornaert B, Carpentier I, Beyaert R. Cellular expression of A20 and ABIN-3 in response to Toll-like receptor-4 stimulation. Methods Mol Biol. 2009;517:205-15 pubmed 出版商
Breckpot K, Aerts Toegaert C, Heirman C, Peeters U, Beyaert R, Aerts J, et al. Attenuated expression of A20 markedly increases the efficacy of double-stranded RNA-activated dendritic cells as an anti-cancer vaccine. J Immunol. 2009;182:860-70 pubmed
Li L, Soetandyo N, Wang Q, Ye Y. The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation. Biochim Biophys Acta. 2009;1793:346-53 pubmed 出版商
Werner S, Kearns J, Zadorozhnaya V, Lynch C, O Dea E, Boldin M, et al. Encoding NF-kappaB temporal control in response to TNF: distinct roles for the negative regulators IkappaBalpha and A20. Genes Dev. 2008;22:2093-101 pubmed 出版商
Li L, Hailey D, Soetandyo N, Li W, Lippincott Schwartz J, Shu H, et al. Localization of A20 to a lysosome-associated compartment and its role in NFkappaB signaling. Biochim Biophys Acta. 2008;1783:1140-9 pubmed 出版商
Coornaert B, Baens M, Heyninck K, Bekaert T, Haegman M, Staal J, et al. T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20. Nat Immunol. 2008;9:263-71 pubmed 出版商
Chevillard G, Derjuga A, Devost D, Zingg H, Blank V. Identification of interleukin-1beta regulated genes in uterine smooth muscle cells. Reproduction. 2007;134:811-22 pubmed
Bohgaki M, Tsukiyama T, Nakajima A, Maruyama S, Watanabe M, Koike T, et al. Involvement of Ymer in suppression of NF-kappaB activation by regulated interaction with lysine-63-linked polyubiquitin chain. Biochim Biophys Acta. 2008;1783:826-37 pubmed
Zhang B, Guan C, Chen W, Zhang P, Yan M, Shi J, et al. A20 inhibits human salivary adenoid cystic carcinoma cells invasion via blocking nuclear factor-kappaB activation. Chin Med J (Engl). 2007;120:1830-5 pubmed
Yokota S, Okabayashi T, Yokosawa N, Fujii N. Measles virus P protein suppresses Toll-like receptor signal through up-regulation of ubiquitin-modifying enzyme A20. FASEB J. 2008;22:74-83 pubmed
Hutti J, Turk B, Asara J, Ma A, Cantley L, Abbott D. IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway. Mol Cell Biol. 2007;27:7451-61 pubmed
Salaun B, Lebecque S, Matikainen S, Rimoldi D, Romero P. Toll-like receptor 3 expressed by melanoma cells as a target for therapy?. Clin Cancer Res. 2007;13:4565-74 pubmed
Wang Y, Li L, Han K, Zhai Z, Shu H. A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter. FEBS Lett. 2004;576:86-90 pubmed
Ke B, Shen X, Lassman C, Gao F, Busuttil R, Kupiec Weglinski J. Cytoprotective and antiapoptotic effects of IL-13 in hepatic cold ischemia/reperfusion injury are heme oxygenase-1 dependent. Am J Transplant. 2003;3:1076-82 pubmed
Yang K, Arcaroli J, Kupfner J, Pitts T, Park J, Strasshiem D, et al. Involvement of phosphatidylinositol 3-kinase gamma in neutrophil apoptosis. Cell Signal. 2003;15:225-33 pubmed
Ke B, Shen X, Zhai Y, Gao F, Busuttil R, Volk H, et al. Heme oxygenase 1 mediates the immunomodulatory and antiapoptotic effects of interleukin 13 gene therapy in vivo and in vitro. Hum Gene Ther. 2002;13:1845-57 pubmed
Wu W, Xu Z, Chang K. The promyelocytic leukemia protein represses A20-mediated transcription. J Biol Chem. 2002;277:31734-9 pubmed
Kupfner J, Arcaroli J, Yum H, Nadler S, Yang K, Abraham E. Role of NF-kappaB in endotoxemia-induced alterations of lung neutrophil apoptosis. J Immunol. 2001;167:7044-51 pubmed
产品信息
品牌 :
Novus
MasterCode :
NBP1-77533
SKU号 :
NBP1-77533
产品名称 :
A20/TNFAIP3 Antibody (59A426) - BSA Free
描述 :
The A20/TNFAIP3 Antibody (59A426) - BSA Free from NBP1-77533 is a nbp1-77533 antibody to . This antibody reacts with cancer, inflammation, innate immunity, necroptosis, neurodegeneration, signal transduction. The A20/TNFAIP3 Antibody (59A426) - BSA Free has been validated for the following applications: P21580.
靶标 :
A20/TNFAIP3
类别 :
一抗
单位尺寸 :
0.1 mg (also 0.025 mg)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
59A426
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Full length recombinant human A20/TNFAIP3 Antibody (59A426). The epitope has been mapped to the C-terminal portion of A20 (amino acids 440-790)
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠
基因符号 :
TNFAIP3
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Western-Blot-NBP1-77533-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Western-Blot-NBP1-77533-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Flow-Cytometry-NBP1-77533-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Flow-Cytometry-NBP1-77533-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Simple-Western-NBP1-77533-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Simple-Western-NBP1-77533-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Immunohistochemistry-Paraffin-NBP1-77533-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Immunohistochemistry-Paraffin-NBP1-77533-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Immunocytochemistry-Immunofluorescence-NBP1-77533-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Immunocytochemistry-Immunofluorescence-NBP1-77533-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Immunocytochemistry-Immunofluorescence-NBP1-77533-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Immunocytochemistry-Immunofluorescence-NBP1-77533-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Flow-Cytometry-NBP1-77533-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/A20-TNFAIP3-Antibody-(59A426)-Flow-Cytometry-NBP1-77533-img0017.jpg
accessionNumbers :
P21580
应用 :
Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Flow (Intracellular), CyTOF-ready
美元 :
469美元
别名 :
A20TNFA1P2, EC 3.4.19.12, EC 6.3.2.-, MGC104522, MGC138687, OTU domain-containing protein 7C, OTUD7CMGC138688, Putative DNA-binding protein A20, TNF alpha-induced protein 3, tumor necrosis factor alpha-induced protein 3, tumor necrosis factor inducible protein A20, tumor necrosis factor, alpha-induced protein 3, Zinc finger protein A20
储存 :
存放在-20C。 避免冻融循环
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。