产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Beclin 1 Antibody - BSA Free
目录 :
NB500-249
规格 :
0.1 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 71
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 5
Obert D, Wolpert A, Grimm N, Korff S. ER stress preconditioning ameliorates liver damage after hemorrhagic shock and reperfusion. Exp Ther Med. 2021;21:248 pubmed 出版商
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Qu W, Jeong A, Zhong R, Thieschafer J, Gram A, Li L. Deletion of Small GTPase H-Ras Rescues Memory Deficits and Reduces Amyloid Plaque-Associated Dendritic Spine Loss in Transgenic Alzheimer's Mice. Mol Neurobiol. 2023;60:495-511 pubmed 出版商
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Nuth M, Benakanakere M, Ricciardi R. Discovery of a potent cytotoxic agent that promotes G2/M phase cell cycle arrest and apoptosis in a malignant human pharyngeal squamous carcinoma cell line. Int J Oncol. 2022;60: pubmed 出版商
Ramasubramanian B, Griffith C, Hanson M, Bunquin L, Reddy A, Hegde V, et al. Protective Effects of Chaya against Mitochondrial and Synaptic Toxicities in the Type 2 Diabetes Mouse Model TallyHO. Cells. 2022;11: pubmed 出版商
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Krunic M, Ristic B, Bosnjak M, Paunovic V, Tovilović Kovačević G, Zogovic N, et al. Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death. Free Radic Biol Med. 2021;177:167-180 pubmed 出版商
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Wen X, Zhang J, Yang W, Nie X, Gui R, Shan D, et al. CircRNA-016901 silencing attenuates irradiation-induced injury in bone mesenchymal stem cells via regulating the miR-1249-5p/HIPK2 axis. Exp Ther Med. 2021;21:355 pubmed 出版商
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Li X, Hu Z, Shi H, Wang C, Lei J, Cheng Y. Inhibition of VEGFA Increases the Sensitivity of Ovarian Cancer Cells to Chemotherapy by Suppressing VEGFA-Mediated Autophagy. Onco Targets Ther. 2020;13:8161-8171 pubmed 出版商
Yefimova M, Lefevre C, Bashamboo A, Eozenou C, Burel A, Lavault M, et al. Granulosa cells provide elimination of apoptotic oocytes through unconventional autophagy-assisted phagocytosis. Hum Reprod. 2020;35:1346-1362 pubmed 出版商
Sacitharan P, Bou Gharios G, Edwards J. SIRT1 directly activates autophagy in human chondrocytes. Cell Death Discov. 2020;6:41 pubmed 出版商
Chen C, Liu L, Shu Y, Jing P, Lu Y, Zhang X, et al. Blockade of HCN2 Channels Provides Neuroprotection Against Ischemic Injury via Accelerating Autophagic Degradation in Hippocampal Neurons. Neurosci Bull. 2020;36:875-894 pubmed 出版商
Lee J, Parveen A, Do M, Kang M, Yumnam S, Kim S. Molecular mechanisms of methylglyoxal-induced aortic endothelial dysfunction in human vascular endothelial cells. Cell Death Dis. 2020;11:403 pubmed 出版商
Dutta K, Thammisetty S, Boutej H, Bareil C, Julien J. Mitigation of ALS Pathology by Neuron-Specific Inhibition of Nuclear Factor Kappa B Signaling. J Neurosci. 2020;40:5137-5154 pubmed 出版商
Zhang R, Li S, Liu L, Yang J, Huang G, Sang Y. TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple. Oncogenesis. 2020;9:45 pubmed 出版商
Cui D, Drake J, Wilson R, Shute R, Lewellen B, Zhang M, et al. A novel voluntary weightlifting model in mice promotes muscle adaptation and insulin sensitivity with simultaneous enhancement of autophagy and mTOR pathway. FASEB J. 2020;34:7330-7344 pubmed 出版商
Fedele A, Proud C. Chloroquine and bafilomycin A mimic lysosomal storage disorders and impair mTORC1 signalling. Biosci Rep. 2020;40: pubmed 出版商
Zhao J, Li G, Zhao X, Lin X, Gao Y, Raimundo N, et al. Down-regulation of AMPK signaling pathway rescues hearing loss in TFB1 transgenic mice and delays age-related hearing loss. Aging (Albany NY). 2020;12:5590-5611 pubmed 出版商
Cursano S, Battaglia C, Urrutia Ruiz C, Grabrucker S, Schön M, Bockmann J, et al. A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome. Mol Psychiatry. 2020;: pubmed 出版商
Urasaki Y, Beaumont C, Workman M, Talbot J, Hill D, Le T. Potency Assessment of CBD Oils by Their Effects on Cell Signaling Pathways. Nutrients. 2020;12: pubmed 出版商
Odeh M, Tamir Livne Y, Haas T, Bengal E. P38α MAPK coordinates the activities of several metabolic pathways that together induce atrophy of denervated muscles. FEBS J. 2020;287:73-93 pubmed 出版商
Gao J, Long L, Xu F, Feng L, Liu Y, Shi J, et al. Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischemia/reperfusion injury by inhibiting GSK-3β-mediated activation of autophagy. Br J Pharmacol. 2019;: pubmed 出版商
Ognibene M, Podesta M, Garaventa A, Pezzolo A. Role of GOLPH3 and TPX2 in Neuroblastoma DNA Damage Response and Cell Resistance to Chemotherapy. Int J Mol Sci. 2019;20: pubmed 出版商
Sun C, Enkhjargal B, Reis C, Zhang T, Zhu Q, Zhou K, et al. Osteopontin-Enhanced Autophagy Attenuates Early Brain Injury via FAK-ERK Pathway and Improves Long-Term Outcome after Subarachnoid Hemorrhage in Rats. Cells. 2019;8: pubmed 出版商
Sun C, Enkhjargal B, Reis C, Zhou K, Xie Z, Wu L, et al. Osteopontin attenuates early brain injury through regulating autophagy-apoptosis interaction after subarachnoid hemorrhage in rats. CNS Neurosci Ther. 2019;25:1162-1172 pubmed 出版商
Tedeschi V, Petrozziello T, Sisalli M, Boscia F, Canzoniero L, Secondo A. The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance. Sci Rep. 2019;9:10743 pubmed 出版商
Chai W, Ye F, Zeng L, Li Y, Yang L. HMGB1-mediated autophagy regulates sodium/iodide symporter protein degradation in thyroid cancer cells. J Exp Clin Cancer Res. 2019;38:325 pubmed 出版商
Roy B, Ahmed I, Ramalingam S, JALA V, Haribabu B, Ramamoorthy P, et al. Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and progression. Oncotarget. 2019;10:2340-2354 pubmed 出版商
Tamrakar S, Yashiro M, Kawashima T, Uda T, Terakawa Y, Kuwae Y, et al. Clinicopathological Significance of Autophagy-related Proteins and its Association With Genetic Alterations in Gliomas. Anticancer Res. 2019;39:1233-1242 pubmed 出版商
Ueno T, Masuda N, Kamigaki S, Morimoto T, Saji S, Imoto S, et al. Differential Involvement of Autophagy and Apoptosis in Response to Chemoendocrine and Endocrine Therapy in Breast Cancer: JBCRG-07TR. Int J Mol Sci. 2019;20: pubmed 出版商
Ye B, Wang Q, Hu H, Shen Y, Fan C, Chen P, et al. Restoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR. Autophagy. 2019;15:998-1016 pubmed 出版商
Houtman J, Freitag K, Gimber N, Schmoranzer J, Heppner F, Jendrach M. Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3. EMBO J. 2019;38: pubmed 出版商
Ugun Klusek A, Theodosi T, Fitzgerald J, Burté F, Ufer C, Boocock D, et al. Monoamine oxidase-A promotes protective autophagy in human SH-SY5Y neuroblastoma cells through Bcl-2 phosphorylation. Redox Biol. 2019;20:167-181 pubmed 出版商
Zhu Y, Fang J, Wang H, Fei M, Tang T, Liu K, et al. Baicalin suppresses proliferation, migration, and invasion in human glioblastoma cells via Ca2+-dependent pathway. Drug Des Devel Ther. 2018;12:3247-3261 pubmed 出版商
Sacitharan P, Lwin S, Gharios G, Edwards J. Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300. Exp Mol Med. 2018;50:123 pubmed 出版商
Dutta K, Patel P, Julien J. Protective effects of Withania somnifera extract in SOD1G93A mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2018;309:193-204 pubmed 出版商
Li D, Wang C, Li Z, Wang H, He J, Zhu J, et al. Nano-sized Al2O3 particle-induced autophagy reduces osteolysis in aseptic loosening of total hip arthroplasty by negative feedback regulation of RANKL expression in fibroblasts. Cell Death Dis. 2018;9:840 pubmed 出版商
Ognibene M, Pagnan G, Marimpietri D, Cangelosi D, Cilli M, Benedetti M, et al. CHL1 gene acts as a tumor suppressor in human neuroblastoma. Oncotarget. 2018;9:25903-25921 pubmed 出版商
Lapierre J, Rodriguez M, Ojha C, El Hage N. Critical Role of Beclin1 in HIV Tat and Morphine-Induced Inflammation and Calcium Release in Glial Cells from Autophagy Deficient Mouse. J Neuroimmune Pharmacol. 2018;13:355-370 pubmed 出版商
Kivinen N. The role of autophagy in age-related macular degeneration. Acta Ophthalmol. 2018;96 Suppl A110:1-50 pubmed 出版商
Li Y, Cai W, Wang L, Liu G, Paul C, Jiang L, et al. Identification of the Functional Autophagy-Regulatory Domain in HCLS1-Associated Protein X-1 That Resists Against Oxidative Stress. DNA Cell Biol. 2018;37:432-441 pubmed 出版商
Lim J, Kim H, Kim M, Kim T, Kim E, Kim Y, et al. Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy. Cell Death Dis. 2018;9:270 pubmed 出版商
Kim Y, Kwak M, Shin J, Hayuningtyas R, Choi J, Shin J. Inflachromene inhibits autophagy through modulation of Beclin 1 activity. J Cell Sci. 2018;131: pubmed 出版商
Guo X, Hu F, Wang H, Fang J, Zhu Z, Wei L, et al. Inhibition of autophagy in hepatocarcinoma cells promotes chemotherapeutic agent-induced apoptosis during nutrient deprivation. Oncol Rep. 2017;: pubmed 出版商
Liu G, Zhu H, Cai W, Wang X, Jiang M, Essandoh K, et al. Regulation of BECN1-Mediated Autophagy by HSPB6: Insights from A Human HSPB6S10F Mutant. Autophagy. 2017;:1-56 pubmed 出版商
Chang R, Li X, Mu N, Hrydziuszko O, Garcia Majano B, Larsson C, et al. MicroRNA expression profiles in non?epithelial ovarian tumors. Int J Oncol. 2018;52:55-66 pubmed 出版商
Ouyang Y, Ning S, Adler J, MacIver B, Knox S, Giffard R. Alteration of Interneuron Immunoreactivity and Autophagic Activity in Rat Hippocampus after Single High-Dose Whole-Brain Irradiation. Cureus. 2017;9:e1414 pubmed 出版商
Li Q, Han Y, Du J, Jin H, Zhang J, Niu M, et al. Alterations of apoptosis and autophagy in developing brain of rats with epilepsy: Changes in LC3, P62, Beclin-1 and Bcl-2 levels. Neurosci Res. 2018;130:47-55 pubmed 出版商
Wang C, Hong Y, Syu J, Tsai Y, Liu X, Chen T, et al. LRWD1 Regulates Microtubule Nucleation and Proper Cell Cycle Progression in the Human Testicular Embryonic Carcinoma Cells. J Cell Biochem. 2018;119:314-326 pubmed 出版商
Rodriguez M, Lapierre J, Ojha C, Kaushik A, Batrakova E, Kashanchi F, et al. Intranasal drug delivery of small interfering RNA targeting Beclin1 encapsulated with polyethylenimine (PEI) in mouse brain to achieve HIV attenuation. Sci Rep. 2017;7:1862 pubmed 出版商
Zhang L, Wang H, Fan Y, Gao Y, Li X, Hu Z, et al. Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways. Sci Rep. 2017;7:46763 pubmed 出版商
Gao Y, Zhuang Z, Gao S, Li X, Zhang Z, Ye Z, et al. Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury. Am J Transl Res. 2017;9:887-899 pubmed
Gelmetti V, De Rosa P, Torosantucci L, Marini E, Romagnoli A, Di Rienzo M, et al. PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation. Autophagy. 2017;13:654-669 pubmed 出版商
Syu J, Baba T, Huang J, Ogawa H, Hsieh C, Hu J, et al. Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth. Sci Rep. 2017;7:240 pubmed 出版商
Huang W, Ao P, Li J, Wu T, Xu L, Deng Z, et al. Autophagy Protects Advanced Glycation End Product-Induced Apoptosis and Expression of MMP-3 and MMP-13 in Rat Chondrocytes. Biomed Res Int. 2017;2017:6341919 pubmed 出版商
Eritja N, Chen B, Rodríguez Barrueco R, Santacana M, Gatius S, Vidal A, et al. Autophagy orchestrates adaptive responses to targeted therapy in endometrial cancer. Autophagy. 2017;13:608-624 pubmed 出版商
Ugun Klusek A, Tatham M, Elkharaz J, Constantin Teodosiu D, Lawler K, Mohamed H, et al. Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway. Cell Death Dis. 2017;8:e2531 pubmed 出版商
Yang Y, Guo C, Liao B, Cao J, Liang C, He X. BAMBI inhibits inflammation through the activation of autophagy in experimental spinal cord injury. Int J Mol Med. 2017;39:423-429 pubmed 出版商
Jang J, Eom J, Jeung H, Cheong J, Lee J, Kim J, et al. AMPK-ULK1-Mediated Autophagy Confers Resistance to BET Inhibitor JQ1 in Acute Myeloid Leukemia Stem Cells. Clin Cancer Res. 2017;23:2781-2794 pubmed 出版商
Park Y, Park J, Ko J, Shin I, Koh H. mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells. Environ Toxicol. 2017;32:109-121 pubmed 出版商
图像
图像 1 :
Novus Biologicals NB500-249 图像 1
Western Blot: Beclin 1 Antibody [NB500-249] - Expression of Beclin 1 mRNA and protein in cells and tissues. (A) Beclin 1 mRNA expression level up-regulated in gastric cancer cell lines compared with normal gastric epithelial cells by reverse transcription-PCR. (B) Beclin 1 protein expression level up-regulated in gastric cancer cell lines compared with normal gastric epithelial cells by western blotting. (C) Beclin 1 mRNA expression is elevated in primary gastric tumors compared with paired gastric adjacent noncancerous tissues by reverse transcription-PCR. (D) Beclin 1 protein expression is elevated in primary gastric tumors compared with paired gastric adjacent noncancerous tissues by western blotting. Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0045968) licensed under a CC-BY licence.
产品信息
品牌 :
Novus
MasterCode :
NB500-249
SKU号 :
NB500-249
产品名称 :
Beclin 1 Antibody - BSA Free
描述 :
The Beclin 1 Antibody - BSA Free from NB500-249 is a nb500-249 antibody to . This antibody reacts with apoptosis, autophagy, cancer, hif target genes, hypoxia, immunology, innate immunity, mtor pathway, tumor suppressors.
靶标 :
Beclin 1
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
Internal synthetic peptide to human Beclin 1, within residues 1-100 [UniProt# Q14457].
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠
基因符号 :
BECN1
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Western-Blot-NB500-249-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Western-Blot-NB500-249-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Immunocytochemistry-Immunofluorescence-NB500-249-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Immunocytochemistry-Immunofluorescence-NB500-249-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Immunohistochemistry-NB500-249-img0020.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Immunohistochemistry-NB500-249-img0020.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Flow-Cytometry-NB500-249-img0024.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Flow-Cytometry-NB500-249-img0024.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin 1 Antibody - BSA Free-Western Blot-NB500-249-img0025.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin 1 Antibody - BSA Free-Western Blot-NB500-249-img0025.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Western-Blot-NB500-249-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Western-Blot-NB500-249-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Immunohistochemistry-Paraffin-NB500-249-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Immunohistochemistry-Paraffin-NB500-249-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Immunohistochemistry-Frozen-NB500-249-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Immunohistochemistry-Frozen-NB500-249-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Flow-Cytometry-NB500-249-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Flow-Cytometry-NB500-249-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Flow-Cytometry-NB500-249-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Flow-Cytometry-NB500-249-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Flow-Cytometry-NB500-249-img0022.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Flow-Cytometry-NB500-249-img0022.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Flow-Cytometry-NB500-249-img0023.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Flow-Cytometry-NB500-249-img0023.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Simple-Western-NB500-249-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Simple-Western-NB500-249-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Knockdown-Validated-NB500-249-img0019.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Beclin-1-Antibody---BSA-Free-Knockdown-Validated-NB500-249-img0019.jpg
应用 :
Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated
美元 :
399美元
别名 :
ATG6, ATG6 autophagy related 6 homolog, beclin 1 (coiled-coil, moesin-like BCL2 interacting protein), beclin 1 (coiled-coil, moesin-like BCL2-interacting protein), beclin 1, autophagy related, beclin1, beclin-1, Coiled-coil myosin-like BCL2-interacting protein, GT197, Protein GT197, VPS30
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。