产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
MRP1 Antibody (IU2H10) - BSA Free
目录 :
NB400-156.1毫升
规格 :
0.1 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
IU2H10
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 16
参考文献
Zhang W, Liu Q, Haqqani A, Liu Z, Sodja C, Leclerc S, et al. Differential Expression of ABC Transporter Genes in Brain Vessels vs. Peripheral Tissues and Vessels from Human, Mouse and Rat. Pharmaceutics. 2023;15: pubmed 出版商
Doganlar O, Doganlar Z, Erdogan S, Delen E. Antineoplastic multi-drug chemotherapy to sensitize tumors triggers multi-drug resistance and inhibits efficiency of maintenance treatment inglioblastoma cells. EXCLI J. 2023;22:35-52 pubmed 出版商
Bhadwal P, Randhawa V, Vaiphei K, Dahiya D, Agnihotri N. Clinical relevance of CERK and SPHK1 in breast cancer and their association with metastasis and drug resistance. Sci Rep. 2022;12:18239 pubmed 出版商
Huang R, Zhu L, Zhang Y. XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way. Cancer Cell Int. 2020;20:436 pubmed 出版商
Sridharan S, Robeson M, Bastihalli Tukaramrao D, Howard C, Subramaniyan B, Tilley A, et al. Targeting of the Eukaryotic Translation Initiation Factor 4A Against Breast Cancer Stemness. Front Oncol. 2019;9:1311 pubmed 出版商
Zhang S, Chatterjee T, Godoy C, Wu L, Liu Q, Carmon K. GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism. Mol Cancer Res. 2019;17:2196-2207 pubmed 出版商
Li K, Ouyang L, He M, Luo M, Cai W, Tu Y, et al. IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway. Oncotarget. 2017;8:28865-28879 pubmed 出版商
Koshkin V, Ailles L, Liu G, Krylov S. Metabolic Suppression of a Drug-Resistant Subpopulation in Cancer Spheroid Cells. J Cell Biochem. 2016;117:59-65 pubmed 出版商
Grybauskas A, Koga T, Kuprys P, Nolan M, McCarty R, Walker L, et al. ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells. Mol Vis. 2015;21:201-12 pubmed
Kurihara Y, Sawazumi T, Takeuchi T. Exploration of interactions between membrane proteins embedded in supported lipid bilayers and their antibodies by reflectometric interference spectroscopy-based sensing. Analyst. 2014;139:6016-21 pubmed 出版商
Chen Y, Lukka P, Joseph W, Finlay G, Paxton J, McKeage M, et al. Selective cellular uptake and retention of SN 28049, a new DNA-binding topoisomerase II-directed antitumor agent. Cancer Chemother Pharmacol. 2014;74:25-35 pubmed 出版商
Tiwari A, Zhang R, Gallo J. Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout mouse models. Mol Cancer Ther. 2013;12:1343-55 pubmed 出版商
Chen Q, Yang Y, Li L, Zhang J. The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function. J Biol Chem. 2006;281:31152-63 pubmed
Binyamin L, Assaraf Y, Reiter Y. Probing ATP-dependent conformational changes in the multidrug resistance protein 1 (MRP1/ABCC1) in live tumor cells with a novel recombinant single-chain Fv antibody targeted to the extracellular N-terminus. Int J Cancer. 2005;116:703-9 pubmed
Yang Y, Chen Q, Zhang J. Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1. J Biol Chem. 2002;277:44268-77 pubmed
Chen Q, Yang Y, Liu Y, Han B, Zhang J. Cytoplasmic retraction of the amino terminus of human multidrug resistance protein 1. Biochemistry. 2002;41:9052-62 pubmed
图像
图像 1 :
Novus Biologicals NB400-156-0.1ml 图像 1
Dual RNAscope ISH-IHC: MRP1 Antibody (IU2H10) [NB400-156] - Formalin-fixed paraffin-embedded tissue sections of human testis were probed for MRP1 mRNA (ACD RNAScope Probe, catalog # 435591; Fast Red chromogen, ACD catalog # 322360). Adjacent tissue section was processed for immunohistochemistry using mouse monoclonal (Novus Biologicals catalog # NB400-156) at 7ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-mouse IgG VisUCyte HRP Polymer Antibody (Catalog # VC001) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to Leydig cells and seminiferous tubule cells.
产品信息
品牌 :
Novus
MasterCode :
NB400-156
SKU号 :
NB400-156.1毫升
产品名称 :
MRP1 Antibody (IU2H10) - BSA Free
描述 :
The MRP1 Antibody (IU2H10) - BSA Free from NB400-156-0.1ml is a nb400-156 antibody to . This antibody reacts with abc transporters, amino acids drugs and other small molecules, cancer, lipid and metabolism, plasma membrane markers, signal transduction.
靶标 :
MRP1
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
IU2H10
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Recombinant peptide (a.a. 1-33) of human MRP1. [UniProt# P33527].
抗体亚型 :
IgG1
纯度 :
蛋白质G纯化
物种 :
人类, 小鼠, 大鼠
基因符号 :
ABCC1
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/MRP1-Antibody-(IU2H10)-Dual-RNAscope-ISH-IHC-NB400-156-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/MRP1-Antibody-(IU2H10)-Dual-RNAscope-ISH-IHC-NB400-156-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/MRP1-Antibody-(IU2H10)-Dual-RNAscope-ISH-IHC-NB400-156-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/MRP1-Antibody-(IU2H10)-Immunocytochemistry-Immunofluorescence-NB400-156-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/MRP1-Antibody-(IU2H10)-Immunocytochemistry-Immunofluorescence-NB400-156-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/MRP1-Antibody-(IU2H10)-Immunocytochemistry-Immunofluorescence-NB400-156-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/MRP1-Antibody-(IU2H10)-Western-Blot-NB400-156-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/MRP1-Antibody-(IU2H10)-Western-Blot-NB400-156-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/MRP1-Antibody-(IU2H10)-Western-Blot-NB400-156-img0006.jpg
应用 :
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, CyTOF-ready, Dual RNAscope ISH-IHC
美元 :
399美元
别名 :
ABC29, ABCC, ATP-binding cassette sub-family C member 1, ATP-binding cassette, sub-family C (CFTR/MRP), member 1, EC 3.6.3, EC 3.6.3.44, GS-X, Leukotriene C(4) transporter, LTC4 transporter, MRP1DKFZp781G125, MRPDKFZp686N04233, multidrug resistance associated protein 1, multidrug resistance protein, multidrug resistance-associated protein 1, multiple drug resistance protein 1, multiple drug resistance-associated protein
储存 :
分成小份儿保存在-20C或-80C。 避免冻融循环
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。