产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
蛋白质前体加工酶9/PCSK9抗体
目录 :
NB300-959
规格 :
0.1毫克
价格 :
399美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
克隆名称 :
39A1413
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 16
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:500; 图 1a
Lebeau P, Byun J, Platko K, Saliba P, Sguazzin M, Macdonald M, et al. Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance. Nat Commun. 2022;13:770 pubmed 出版商
Wen Z, Tang Z, Gu L, Xiang X, Qu Y. Immunomodulatory effect of low molecular-weight seleno-aminopolysaccharide on immunosuppressive mice. Int J Biol Macromol. 2019;123:1278-1288 pubmed 出版商
Tanaka H, Inuzuka K, Iida Y, Shimizu H, Unno N, Urano T. Proprotein Convertase Subtilisin/Kexin Type 9 Is Associated with Degenerating Adipocytes in Abdominal Aortic Aneurysm. J Oleo Sci. 2018;67:1355-1360 pubmed 出版商
Lebeau P, Platko K, Al Hashimi A, Byun J, Lhotak S, Holzapfel N, et al. Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained. J Biol Chem. 2018;293:7329-7343 pubmed 出版商
Kanno Y, Maruyama C, Matsuda A, Ishisaki A. uPA-derived peptide, Å6 is involved in the suppression of lipopolysaccaride-promoted inflammatory osteoclastogenesis and the resultant bone loss. Immun Inflamm Dis. 2017;5:289-299 pubmed 出版商
Gu L, Wen Z, Xiang X, Ma L, Wang X, Ma J, et al. Immunomodulatory effect of low molecular-weight seleno-aminopolysaccharides in intestinal epithelial cells. Int J Biol Macromol. 2017;99:570-577 pubmed 出版商
Lebeau P, Al Hashimi A, Sood S, Lhotak S, Yu P, Gyulay G, et al. Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism. J Biol Chem. 2017;292:1510-1523 pubmed 出版商
Samanta D, Gilkes D, Chaturvedi P, Xiang L, Semenza G. Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells. Proc Natl Acad Sci U S A. 2014;111:E5429-38 pubmed 出版商
Das U, Manna K, Sinha M, Datta S, Das D, Chakraborty A, et al. Role of ferulic acid in the amelioration of ionizing radiation induced inflammation: a murine model. PLoS ONE. 2014;9:e97599 pubmed 出版商
Shakibaei M, Allaway D, Nebrich S, Mobasheri A. Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1?-Induced NF-?B Activation in Canine Articular Chondrocytes. Evid Based Complement Alternat Med. 2012;2012:509383 pubmed 出版商
Li Q, Guo Y, Tan W, Ou Q, Wu W, Sturza D, et al. Cardioprotection afforded by inducible nitric oxide synthase gene therapy is mediated by cyclooxygenase-2 via a nuclear factor-kappaB dependent pathway. Circulation. 2007;116:1577-84 pubmed
Yang M, Hase H, Legarda Addison D, Varughese L, Seed B, Ting A. B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells. J Immunol. 2005;175:2814-24 pubmed
Jazirehi A, Huerta Yepez S, Cheng G, Bonavida B. Rituximab (chimeric anti-CD20 monoclonal antibody) inhibits the constitutive nuclear factor-{kappa}B signaling pathway in non-Hodgkin's lymphoma B-cell lines: role in sensitization to chemotherapeutic drug-induced apoptosis. Cancer Res. 2005;65:264-76 pubmed
Lotz S, Aga E, Wilde I, van Zandbergen G, Hartung T, Solbach W, et al. Highly purified lipoteichoic acid activates neutrophil granulocytes and delays their spontaneous apoptosis via CD14 and TLR2. J Leukoc Biol. 2004;75:467-77 pubmed
Ikezoe T, Yang Y, Heber D, Taguchi H, Koeffler H. PC-SPES: a potent inhibitor of nuclear factor-kappa B rescues mice from lipopolysaccharide-induced septic shock. Mol Pharmacol. 2003;64:1521-9 pubmed
Han H, Karabiyikoglu M, Kelly S, Sobel R, Yenari M. Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke. J Cereb Blood Flow Metab. 2003;23:589-98 pubmed
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB300-959
SKU号 :
NB300-959
产品名称 :
蛋白质前体加工酶9/PCSK9抗体
描述 :
The Proprotein Convertase 9/PCSK9 Antibody from Novus is a goat polyclonal antibody to Proprotein Convertase 9/PCSK9. This antibody reacts with human, mouse. The Proprotein Convertase 9/PCSK9 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Peptide ELISA, Chromatin Immunoprecipitation (ChIP).
靶标 :
蛋白质前体加工酶9/PCSK9
类别 :
一抗
单位尺寸 :
0.1毫克
缓冲液 :
三羟甲基氨基甲烷盐溶液(20 mM三羟甲基氨基甲烷pH值7.3, 150 mM氯化钠), 0.5% BSA
克隆性 :
多克隆
浓度 :
0.5毫克/毫升
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Peptide with sequence CRSRHLAQASQELQ corresponding to C-Terminus according to NP_777596.2.
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠
基因符号 :
PCSK9
accessionNumbers :
Q8NBP7
应用 :
免疫印迹, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡, 肽酶联免疫吸附测定, 染色质免疫沉淀 (ChIP)
美元 :
399美元
别名 :
EC 3.4.21, EC 3.4.21.111, FH3neural apoptosis regulated convertase 1, HCHOLA3, hypercholesterolemia, autosomal dominant 3, LDLCQ1, NARC-1convertase subtilisin/kexin type 9 preproprotein, NARC1EC 3.4.21.-, Neural apoptosis-regulated convertase 1, PC9, Proprotein convertase 9, proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9
储存 :
存放在-20C。 避免冻融循环
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。