产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
p53 Antibody (PAb 240) - BSA Free
目录 :
NB200-103
规格 :
0.1 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
多克隆抗体240
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 39
出版应用/物种/样本/稀释 | 参考文献 |
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| Jensen M, Factor V, Fantozzi A, Helin K, Huh C, Thorgeirsson S. Reduced hepatic tumor incidence in cyclin G1-deficient mice. Hepatology. 2003;37:862-70 pubmed
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| Asher G, Lotem J, Cohen B, Sachs L, Shaul Y. Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1. Proc Natl Acad Sci U S A. 2001;98:1188-93 pubmed
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| Jones N, Turner J, McIlwrath A, Brown R, Dive C. Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53. Mol Pharmacol. 1998;53:819-26 pubmed
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| Halazonetis T, Davis L, Kandil A. Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA. EMBO J. 1993;12:1021-8 pubmed
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| Rubio M, von Deimling A, Yandell D, Wiestler O, Gusella J, Louis D. Accumulation of wild type p53 protein in human astrocytomas. Cancer Res. 1993;53:3465-7 pubmed
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| Bargonetti J, Manfredi J, Chen X, Marshak D, Prives C. A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein. Genes Dev. 1993;7:2565-74 pubmed
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| Davidoff A, Humphrey P, Iglehart J, Marks J. Genetic basis for p53 overexpression in human breast cancer. Proc Natl Acad Sci U S A. 1991;88:5006-10 pubmed
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| Georgoff I, Martinez J, Levine A. Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Genes Dev. 1991;5:151-9 pubmed
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| Gannon J, Greaves R, Iggo R, Lane D. Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. EMBO J. 1990;9:1595-602 pubmed
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| Cunningham J, Lust J, Schaid D, Bren G, Carpenter H, Rizza E, et al. Expression of p53 and 17p allelic loss in colorectal carcinoma. Cancer Res. 1992;52:1974-80 pubmed
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| Remvikos Y, Tominaga O, Hammel P, Laurent Puig P, Salmon R, Dutrillaux B, et al. Increased p53 protein content of colorectal tumours correlates with poor survival. Br J Cancer. 1992;66:758-64 pubmed
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| Somers K, Merrick M, Lopez M, Incognito L, Schechter G, Casey G. Frequent p53 mutations in head and neck cancer. Cancer Res. 1992;52:5997-6000 pubmed
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| Eccles D, Brett L, Lessells A, Gruber L, Lane D, Steel C, et al. Overexpression of the p53 protein and allele loss at 17p13 in ovarian carcinoma. Br J Cancer. 1992;65:40-4 pubmed
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Shi M, Ma L, Zhou L, Fu P. Renal Protective Effects of 17β-Estradiol on Mice with Acute Aristolochic Acid Nephropathy. Molecules. 2016;21: pubmed
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Blagosklonny M, Toretsky J, Bohen S, Neckers L. Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90. Proc Natl Acad Sci U S A. 1996;93:8379-83 pubmed
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Farrell P, Allan G, Shanahan F, Vousden K, Crook T. p53 is frequently mutated in Burkitt's lymphoma cell lines. EMBO J. 1991;10:2879-87 pubmed
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产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB200-103
SKU号 :
NB200-103
产品名称 :
p53 Antibody (PAb 240) - BSA Free
描述 :
The p53 Antibody (PAb 240) - BSA Free from Novus is a mouse monoclonal antibody to p53. This antibody reacts with human, mouse, rat, yeast, xenopus (negative). The p53 Antibody (PAb 240) - BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular), CyTOF-ready.
靶标 :
p53
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
单克隆
克隆 :
多克隆抗体240
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Gel-purified p53-beta-galactosidase fusion protein containing murine p53 from aa 14-389 (derived from pSV53C cDNA clone).
抗体亚型 :
IgG1 Kappa
纯度 :
蛋白质G纯化
物种 :
Human, Mouse, Rat, Yeast, Xenopus (Negative)
特异性 :
This monoclonal recognizes both mutant forms and wild-type human p53 under denaturing conditions
基因符号 :
TP53
应用 :
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular), CyTOF-ready
美元 :
399美元
别名 :
Antigen NY-CO-13, FLJ92943, LFS1TRP53, p53, p53 tumor suppressor, P53cellular tumor antigen p53, Phosphoprotein p53, transformation-related protein 53, tumor protein p53, Tumor suppressor p53
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/9.jpg)
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。