产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
TRPA1 Antibody - BSA Free
目录 :
NB110-40763
规格 :
0.1 ml (also 0.025 ml)
价格 :
469美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
Alexa Fluor系列荧光染料405
克隆名称 :
711-66
反应物种 :
人类, 小鼠, 大鼠, 斑马鱼
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 56
参考文献
Luostarinen S, H xe4 m xe4 l xe4 inen M, Pemmari A, Moilanen E. The regulation of TRPA1 expression and function by Th1 and Th2-type inflammation in human A549 lung epithelial cells. Inflamm Res. 2023;72:1327-1339 pubmed 出版商
Wang M, Zhao M, Xu S, Zheng Z, Zhang J, Pan W, et al. TRPA1 deficiency attenuates cardiac fibrosis via regulating GRK5/NFAT signaling in diabetic rats. Biochem Pharmacol. 2023;214:115671 pubmed 出版商
Pandey M, Zhang J, Adikaram P, Kittock C, Lue N, Awe A, et al. Specific regulation of mechanical nociception by Gβ5 involves GABA-B receptors. JCI Insight. 2023;8: pubmed 出版商
Pereira G, Piton E, Bornholdt J, Dos Santos B, de Almeida A, Dalenogare D, et al. TRPA1 participation in behavioral impairment induced by chronic corticosterone administration. Psychopharmacology (Berl). 2023;240:157-169 pubmed 出版商
Yang N, Shao H, Deng J, Yang Y, Tang Z, Wu G, et al. Dictamnine ameliorates chronic itch in DNFB-induced atopic dermatitis mice via inhibiting MrgprA3. Biochem Pharmacol. 2023;208:115368 pubmed 出版商
S xe1 nchez J, Mu xf1 oz L, Galindo M xe1 rquez M, Valencia V xe1 squez A, Garc xed a A. Paclitaxel Regulates TRPA1 Function and Expression Through PKA and PKC. Neurochem Res. 2023;48:295-304 pubmed 出版商
Kusiak A, Jakubowska M, Stopa K, Zhang X, Huang W, Gerasimenko J, et al. Activation of pancreatic stellate cells attenuates intracellular Ca2+ signals due to downregulation of TRPA1 and protects against cell death induced by alcohol metabolites. Cell Death Dis. 2022;13:744 pubmed 出版商
Vasavda C, Xu R, Liew J, Kothari R, Dhindsa R, Semenza E, et al. Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain. Sci Adv. 2022;8:eabo5633 pubmed 出版商
Lowin T, Laaser S, Kok C, Bruneau E, Pongratz G. Cannabidiol: Influence on B Cells, Peripheral Blood Mononuclear Cells, and Peripheral Blood Mononuclear Cell/Rheumatoid Arthritis Synovial Fibroblast Cocultures. Cannabis Cannabinoid Res. 2022;: pubmed 出版商
Marcotti A, Fern xe1 ndez Trillo J, Gonz xe1 lez A, Vizca xed no Escoto M, Ros Arlanz xf3 n P, Romero L, et al. TRPA1 modulation by Sigma-1 receptor prevents oxaliplatin-induced painful peripheral neuropathy. Brain. 2022;: pubmed 出版商
Zhu H, Wang Y, He Y, Yu W. Inflammation-mediated macrophage polarization induces TRPV1/TRPA1 heteromers in endometriosis. Am J Transl Res. 2022;14:3066-3078 pubmed
Chen Y, Lian Y, Chen W, Chang C, Tinkov A, Skalny A, et al. Lycium barbarum Polysaccharides and Capsaicin Inhibit Oxidative Stress, Inflammatory Responses, and Pain Signaling in Rats with Dextran Sulfate Sodium-Induced Colitis. Int J Mol Sci. 2022;23: pubmed 出版商
Kiss F, Kormos V, Sz x151 ke x, Kecsk xe9 s A, T xf3 th N, Steib A, et al. Functional Transient Receptor Potential Ankyrin 1 and Vanilloid 1 Ion Channels Are Overexpressed in Human Oral Squamous Cell Carcinoma. Int J Mol Sci. 2022;23: pubmed 出版商
Yang X, Ling S, Zhou M, Deng H, Qi M, Liu X, et al. Inhibition of TRPA1 Attenuates Oxidative Stress-induced Damage After Traumatic Brain Injury via the ERK/AKT Signaling Pathway. Neuroscience. 2022;494:51-68 pubmed 出版商
Szab xf3 K, Kem xe9 ny x, Bal xe1 zs N, Khanfar E, S xe1 ndor Z, Boldizs xe1 r F, et al. Presence of TRPA1 Modifies CD4+/CD8+ T Lymphocyte Ratio and Activation. Pharmaceuticals (Basel). 2022;15: pubmed 出版商
Liu Q, Feng L, Han X, Zhang W, Zhang H, Xu L. The TRPA1 Channel Mediates Mechanical Allodynia and Thermal Hyperalgesia in a Rat Bone Cancer Pain Model. Front Pain Res (Lausanne). 2021;2:638620 pubmed 出版商
Chen L, Lee M, Chang C, Liou K, Liu S, Chern C, et al. Suppression of Inflammatory and Fibrotic Signals by Cinnamon (Cinnamomum cassia) and Cinnamaldehyde in Cyclophosphamide-Induced Overactive Bladder in Mice. Evid Based Complement Alternat Med. 2021;2021:5205759 pubmed 出版商
Chen C, Huang X, Zhu W, Ding C, Huang P, Li R. TRPA1 triggers hyperalgesia and inflammation after tooth bleaching. Sci Rep. 2021;11:17418 pubmed 出版商
Luostarinen S, Hamalainen M, Hatano N, Muraki K, Moilanen E. The inflammatory regulation of TRPA1 expression in human A549 lung epithelial cells. Pulm Pharmacol Ther. 2021;70:102059 pubmed 出版商
Chen L, Liu S, Xiao L, Chen K, Tang J, Huang C, et al. An initial assessment of the involvement of transglutaminase2 in eosinophilic bronchitis using a disease model developed in C57BL/6 mice. Sci Rep. 2021;11:11946 pubmed 出版商
Guan M, Ying S, Wang Y. Increased expression of transient receptor potential channels and neurogenic factors associates with cough severity in a guinea pig model. BMC Pulm Med. 2021;21:187 pubmed 出版商
Wamba B, Ghosh P, Mbaveng A, Bhattacharya S, Debarpan M, Depanwita S, et al. Botanical from Piper capense Fruit Can Help to Combat the Melanoma as Demonstrated by In Vitro and In Vivo Studies. Evid Based Complement Alternat Med. 2021;2021:8810368 pubmed 出版商
Huang H, Tay S, Ng W, Ng S, Soong T. Targeting novel human transient receptor potential ankyrin 1 splice variation with splice-switching antisense oligonucleotides. Pain. 2021;162:2097-2109 pubmed 出版商
Shi L, Lin Y, Jiao Y, Herr S, Tang J, Rogers E, et al. Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson's disease: implication of acrolein and TRPA1. Transl Neurodegener. 2021;10:13 pubmed 出版商
Chen Y, Wang Z, Yeo M, Zhang Q, López Romero A, Ding H, et al. Epithelia-Sensory Neuron Cross Talk Underlies Cholestatic Itch Induced by Lysophosphatidylcholine. Gastroenterology. 2021;161:301-317.e16 pubmed 出版商
Oguri G, Nakajima T, Kikuchi H, Obi S, Nakamura F, Komuro I. Allyl isothiocyanate (AITC) activates nonselective cation currents in human cardiac fibroblasts: possible involvement of TRPA1. Heliyon. 2021;7:e05816 pubmed 出版商
Wang S, Qi S, Kogure Y, Kanda H, Tian L, Yamamoto S, et al. The ubiquitin E3 ligase Nedd4-2 relieves mechanical allodynia through the ubiquitination of TRPA1 channel in db/db mice. Eur J Neurosci. 2021;53:1691-1704 pubmed 出版商
Chen Z, Luo J, Li J, Kim G, Stewart A, Urban J, et al. Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis. Immunity. 2021;54:151-163.e6 pubmed 出版商
Nummenmaa E, Hamalainen M, Pemmari A, Moilanen L, Tuure L, Nieminen R, et al. Transient Receptor Potential Ankyrin 1 (TRPA1) Is Involved in Upregulating Interleukin-6 Expression in Osteoarthritic Chondrocyte Models. Int J Mol Sci. 2020;22: pubmed 出版商
Van Liefferinge E, Van Noten N, Degroote J, Vrolix G, Van Poucke M, Peelman L, et al. Expression of Transient Receptor Potential Ankyrin 1 and Transient Receptor Potential Vanilloid 1 in the Gut of the Peri-Weaning Pig Is Strongly Dependent on Age and Intestinal Site. Animals (Basel). 2020;10: pubmed 出版商
Li Q, Ma T, Qiu Y, Cui W, Chen T, Zhang W, et al. Connexin 36 Mediates Orofacial Pain Hypersensitivity Through GluK2 and TRPA1. Neurosci Bull. 2020;36:1484-1499 pubmed 出版商
Virk H, Rekas M, Biddle M, Wright A, Sousa J, Weston C, et al. Validation of antibodies for the specific detection of human TRPA1. Sci Rep. 2019;9:18500 pubmed 出版商
Sahoo S, Majhi R, Tiwari A, Acharya T, Kumar P, Saha S, et al. Transient receptor potential ankyrin1 channel is endogenously expressed in T cells and is involved in immune functions. Biosci Rep. 2019;39: pubmed 出版商
Brandolini L, Castelli V, Aramini A, Giorgio C, Bianchini G, Russo R, et al. DF2726A, a new IL-8 signalling inhibitor, is able to counteract chemotherapy-induced neuropathic pain. Sci Rep. 2019;9:11729 pubmed 出版商
Ma S, Zhang Y, He K, Wang P, Wang D. Knockout of TRPA1 exacerbates angiotensin II-induced kidney injury. Am J Physiol Renal Physiol. 2019;317:F623-F631 pubmed 出版商
Miao F, Wang R, Cui G, Li X, Wang T, Li X. Engagement of MicroRNA-155 in Exaggerated Oxidative Stress Signal and TRPA1 in the Dorsal Horn of the Spinal Cord and Neuropathic Pain During Chemotherapeutic Oxaliplatin. Neurotox Res. 2019;: pubmed 出版商
Kameda T, Zvick J, Vuk M, Sadowska A, Tam W, Leung V, et al. Expression and Activity of TRPA1 and TRPV1 in the Intervertebral Disc: Association with Inflammation and Matrix Remodeling. Int J Mol Sci. 2019;20: pubmed 出版商
CONKLIN D, Guo Y, Nystoriak M, Jagatheesan G, Obal D, Kilfoil P, et al. TRPA1 channel contributes to myocardial ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 2019;316:H889-H899 pubmed 出版商
Ma W, Chen X, Cerne R, Syed S, Ficorilli J, Cabrera O, et al. Catechol estrogens stimulate insulin secretion in pancreatic β-cells via activation of the transient receptor potential A1 (TRPA1) channel. J Biol Chem. 2019;294:2935-2946 pubmed 出版商
Peixoto Neves D, Soni H, Adebiyi A. CGRPergic Nerve TRPA1 Channels Contribute to Epigallocatechin Gallate-Induced Neurogenic Vasodilation. ACS Chem Neurosci. 2019;10:216-220 pubmed 出版商
Wang Z, Xu Y, Wang M, Ye J, Liu J, Jiang H, et al. TRPA1 inhibition ameliorates pressure overload-induced cardiac hypertrophy and fibrosis in mice. EBioMedicine. 2018;36:54-62 pubmed 出版商
Takahashi N, Chen H, Harris I, Stover D, Selfors L, Bronson R, et al. Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance. Cancer Cell. 2018;33:985-1003.e7 pubmed 出版商
Lowin T, Bleck J, Schneider M, Pongratz G. Selective killing of proinflammatory synovial fibroblasts via activation of transient receptor potential ankyrin (TRPA1). Biochem Pharmacol. 2018;154:293-302 pubmed 出版商
De Logu F, Nassini R, Materazzi S, Carvalho Gonçalves M, Nosi D, Rossi Degl Innocenti D, et al. Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice. Nat Commun. 2017;8:1887 pubmed 出版商
Matsuda K, Okamoto N, Kondo M, Arkwright P, Karasawa K, Ishizaka S, et al. Mast cell hyperactivity underpins the development of oxygen-induced retinopathy. J Clin Invest. 2017;127:3987-4000 pubmed 出版商
Nummenmaa E, Hamalainen M, Moilanen L, Moilanen T, Vuolteenaho K, Moilanen E. TRPA1 expression is downregulated by dexamethasone and aurothiomalate in human chondrocytes: TRPA1 as a novel factor and drug target in arthritis. RMD Open. 2017;3:e000556 pubmed 出版商
Chen J, Ping Y, Tseng M, Chang Y, Lee H, Hsieh R, et al. Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation. Sci Rep. 2017;7:42883 pubmed 出版商
Hidaka T, Ogawa E, Kobayashi E, Suzuki T, Funayama R, Nagashima T, et al. The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin. Nat Immunol. 2017;18:64-73 pubmed 出版商
Lu Y, Piplani H, McAllister S, Hurt C, Gross E. Transient Receptor Potential Ankyrin 1 Activation within the Cardiac Myocyte Limits Ischemia-reperfusion Injury in Rodents. Anesthesiology. 2016;125:1171-1180 pubmed
Nummenmaa E, Hamalainen M, Moilanen L, Paukkeri E, Nieminen R, Moilanen T, et al. Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in primary human osteoarthritic chondrocytes. Arthritis Res Ther. 2016;18:185 pubmed 出版商
Lee K, Lin H, Lee H, Tsai F, Lee T. Loss of Transient Receptor Potential Ankyrin 1 Channel Deregulates Emotion, Learning and Memory, Cognition, and Social Behavior in Mice. Mol Neurobiol. 2017;54:3606-3617 pubmed 出版商
Lee K, Lee H, Lin H, Tsay H, Tsai F, Shyue S, et al. Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease. J Neuroinflammation. 2016;13:92 pubmed 出版商
Takaya J, Mio K, Shiraishi T, Kurokawa T, Otsuka S, Mori Y, et al. A Potent and Site-Selective Agonist of TRPA1. J Am Chem Soc. 2015;137:15859-64 pubmed 出版商
Billeter A, Galbraith N, Walker S, Lawson C, Gardner S, Sarojini H, et al. TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response. Surgery. 2015;158:646-54 pubmed 出版商
Weng H, Patel K, Jeske N, Bierbower S, Zou W, Tiwari V, et al. Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 2015;85:833-46 pubmed 出版商
Terada Y, Fujimura M, Nishimura S, Tsubota M, Sekiguchi F, Kawabata A. Roles of Cav3.2 and TRPA1 channels targeted by hydrogen sulfide in pancreatic nociceptive processing in mice with or without acute pancreatitis. J Neurosci Res. 2015;93:361-9 pubmed 出版商
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB110-40763
SKU号 :
NB110-40763
产品名称 :
TRPA1 Antibody - BSA Free
描述 :
The TRPA1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to TRPA1. This antibody reacts with human, mouse, rat, guinea pig, zebrafish. The TRPA1 Antibody - BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
靶标 :
TRPA1
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
A synthetic peptide made to a region within the N-terminus (residues 1-100) of the human TRPA1 protein. [Swiss-Prot# O75762]
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠, 豚鼠, 斑马鱼
特异性 :
Additional modified form of TRPA1 can also be detected
理论上的分子量 :
127.5 kDa
基因符号 :
TRPA1
accessionNumbers :
O75762
应用 :
免疫印迹, 流式细胞仪, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡, 免疫组化冷冻
美元 :
469美元
别名 :
ANKTM1ankyrin-like with transmembrane domains 1, Ankyrin-like with transmembrane domains protein 1, Transformation-sensitive protein p120, transient receptor potential cation channel subfamily A member 1, transient receptor potential cation channel, subfamily A, member 1
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。