蛋白

重组人类微管蛋白乙4A链(TUBB4A)

MBS964614

0.01毫克(酵母)

140美元

重组蛋白

重组人类微管蛋白乙4A链(TUBB4A)

微管蛋白乙4A链

微管蛋白5乙;微管蛋白乙4链

tubulin beta-4A chain isoform 1; Tubulin beta-4A chain; tubulin beta-4A chain; tubulin beta 4A class IVa; Tubulin 5 beta; Tubulin beta-4 chain

TUBB4A

TUBB4A;TUBB4A;DYT4;TUBB4;乙5;TUBB4;TUBB5

TBB4A_HUMAN

E Coli or Yeast or Baculovirus or Mammalian Cell

1-444

495

MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGD
SDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRS
GPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVL
DVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIR
EEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVEN
TDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMS
GVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPL
TSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT
VAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKT
AVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR
RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAT
AEEGEFEEEAEEEVA

Greater than 90% as determined by SDS-PAGE.

Liquid containing glycerol; lyophilization may be available upon request.

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Species: Homo sapiens (Human)

信号转导

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Sequence of an expressed human beta-tubulin gene containing ten Alu family members." Lee M.G.-S., Loomis C., Cowan N.J. Nucleic Acids Res. 12:5823-5836(1984)

574584803

NP_001276052.1

NM_001289123.1

P04350

53.65kD

Anchoring Of The Basal Body To The Plasma Membrane Pathway (1268847); Assembly Of The Primary Cilium Pathway (1268846); Cell Cycle Pathway (1269741); Cell Cycle, Mitotic Pathway (1269763); Centrosome Maturation Pathway (1269805); Chaperonin-mediated Protein Folding Pathway (1268694); Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway (1268695); Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway (1268697); G2/M Transition Pathway (1269799); Gap Junction Pathway (83072)

This gene encodes a member of the beta tubulin family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene cause hypomyelinating leukodystrophy-6 and autosomal dominant torsion dystonia-4. Alternate splicing results in multiple transcript variants encoding different isoforms. A pseudogene of this gene is found on chromosome X. [provided by RefSeq, Jan 2014]

TUBB4: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: cell soma; cilium; cytosol; internode region of axon; microtubule; myelin sheath; nucleus. Molecular Function: GTP binding; GTPase activity; protein binding; structural constituent of cytoskeleton. Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; G2/M transition of mitotic cell cycle; microtubule-based process; mitotic cell cycle; organelle organization and biogenesis; protein folding. Disease: Dystonia 4, Torsion, Autosomal Dominant

0.01毫克(酵母)

140美元

0.05毫克(酵母)

245

0.2毫克(酵母)

605

0.5毫克(酵母)

990

1毫克(酵母)

1550