产品简要
公司名称 :
MyBioSource
产品类型 :
蛋白
产品名称 :
Recombinant Mouse Protein phosphatase 1 regulatory subunit 15A (Ppp1r15a)
目录 :
MBS963288
规格 :
0.5毫克(大肠杆菌)
价格 :
1455美元
更多信息或购买 :
产品信息
目录号 :
MBS963288
产品类型 :
重组蛋白
产品全称 :
Recombinant Mouse Protein phosphatase 1 regulatory subunit 15A (Ppp1r15a)
产品简称 :
Protein phosphatase 1 regulatory subunit 15A (Ppp1r15a)
产品名称同义词 :
Protein phosphatase 1 regulatory subunit 15A; Growth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116
其他名称 :
protein phosphatase 1 regulatory subunit 15A; Protein phosphatase 1 regulatory subunit 15A; protein phosphatase 1 regulatory subunit 15A; growth arrest and DNA-damage-inducible 34; myeloid differentiation primary response gene 116; growth arrest and DNA damage-inducible protein GADD34; myeloid differentiation primary response protein MyD116; protein phosphatase 1, regulatory (inhibitor) subunit 15A; Growth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116
产品基因名称 :
Ppp1r15a
产品基因名称同义词 :
Ppp1r15a;Gadd34;Myd116
其他基因名称 :
Ppp1r15a;Ppp1r15a;Gadd34;Myd116;9630030H21;Gadd34;Myd116
UniProt数据库进入名 :
PR15A_MOUSE
宿主 :
E Coli or Yeast or Baculovirus or Mammalian Cell
序列位置 :
1-657
序列长度 :
657
序列 :
MAPSPRPQHV LHWRDAHNFY LLSPLMGLLS RAWSRLRGPE VPEAWLAKTV TGADQIEAAA LLTPTPVSGN LLPHGETEES GSPEQSQAAQ RLCLVEAESS PPETWGLSNV DEYNAKPGQD DLREKEMERT AGKATLQPAG LQGADKRLGE VVAREEGVAE PAYPTSQLEG GPAENEEDGE TVKTYQASAA SIAPGYKPST PVPFLGEAEH QATEEKGTEN KADPSNSPSS GSHSRAWEYY SREKPKQEGE AKVEAHRAGQ GHPCRNAEAE EGGPETTFVC TGNAFLKAWV YRPGEDTEEE DNSDSDSAEE DTAQTGATPH TSAFLKAWVY RPGEDTEEED SDSDSAEEDT AQTGATPHTS AFLKAWVYRP GEDTEEENSD LDSAEEDTAQ TGATPHTSAF LKAWVYRPGE DTEEENSDLD SAEEDTAQTG ATPHTSPFLK AWVYRPGEDT EDDTEEEEDS ENVAPGDSET ADSSQSPCLQ PQRCLPGEKT KGRGEEPPLF QVAFYLPGEK PESPWAAPKL PLRLQRRLRL FKAPTRDQDP EIPLKARKVH FAEKVTVHFL AVWAGPAQAA RRGPWEQFAR DRSRFARRIA QAEEKLGPYL TPDSRARAWA RLRNPSLPQS EPRSSSEATP LTQDVTTPSP LPSETPSPSL YLGGRRG
纯度 :
>90%
形式 :
Liquid containing glycerol; lyophilization may be available upon request.
储存稳定性 :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
其它信息1 :
Species: Mus musculus (Mouse)
NCBI GI登录号 :
6678978
NCBI登录号 :
NP_032680.1
NCBI基因登录号 :
NM_008654.2
UniProt数据库登录号 :
P17564
NCBI分子量 :
63,474 Da
NCBI信号通路 :
Downregulation Of TGF-beta Receptor Signaling Pathway (819823); Protein Processing In Endoplasmic Reticulum Pathway (167331); Protein Processing In Endoplasmic Reticulum Pathway (167190); Signal Transduction Pathway (819739); Signaling By TGF-beta Receptor Complex Pathway (819821); TGF-beta Receptor Signaling Activates SMADs Pathway (819822)
UniProt数据库总结 :
GADD34: Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on Ser-15 . Belongs to the PPP1R15 family. Protein type: DNA repair, damage; Cell cycle regulation; Apoptosis; Translation initiation. Cellular Component: Golgi apparatus; mitochondrial outer membrane; mitochondrion; membrane; endoplasmic reticulum; cytoplasm; protein phosphatase type 1 complex. Molecular Function: protein phosphatase regulator activity; protein kinase binding; protein phosphatase binding; protein phosphatase 1 binding. Biological Process: regulation of translation; positive regulation of phosphoprotein phosphatase activity; negative regulation of protein amino acid dephosphorylation; unfolded protein response; apoptosis; negative regulation of phosphoprotein phosphatase activity; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription from RNA polymerase I promoter
尺寸1 :
0.5毫克(大肠杆菌)
价格1 :
1455美元
尺寸2 :
0.05毫克(杆状病毒)
价格2 :
1455
size3 :
0.5毫克(酵母)
价格3 :
1685
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1685
size5 :
1毫克(大肠杆菌)
price5 :
2480
更多信息或购买 :
公司信息
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MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。