产品简要
公司名称 :
MyBioSource
产品类型 :
蛋白
产品名称 :
重组人类硫氧还蛋白(TXN)
目录 :
MBS960600
规格 :
0.5毫克(大肠杆菌)
价格 :
835美元
更多信息或购买 :
产品信息
目录号 :
MBS960600
产品类型 :
重组蛋白
产品全称 :
重组人类硫氧还蛋白(TXN)
产品简称 :
硫氧还蛋白(TXN)
产品名称同义词 :
Thioredoxin; Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP
其他名称 :
thioredoxin isoform 2; Thioredoxin; thioredoxin; ADF; SASP; TXN delta 3; ATL-derived factor; thioredoxin delta 3; surface-associated sulphydryl protein; thioredoxin; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP
产品基因名称 :
TXN
产品基因名称同义词 :
TXN;TRDX;TRX;TRX1
其他基因名称 :
TXN; TXN; TRX; TRDX; TRX1; TRDX; TRX; TRX1; Trx; ADF; SASP
UniProt数据库进入名 :
THIO_HUMAN
宿主 :
E Coli or Yeast or Baculovirus or Mammalian Cell
序列位置 :
2-105
序列长度 :
104
序列 :
VKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT INELV
纯度 :
>90%
形式 :
Liquid containing glycerol; lyophilization may be available upon request.
储存稳定性 :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
其它信息1 :
Species: Homo sapiens (Human)
NCBI GI登录号 :
349732256
NCBI登录号 :
NP_001231867.1
NCBI基因登录号 :
NM_001244938.1
UniProt数据库登录号 :
P10599
NCBI分子量 :
9,452 Da
NCBI信号通路 :
Folic Acid Network Pathway (219799); Folic Acid Network Pathway (198383); Immune System Pathway (106386); Inflammasomes Pathway (366166); Innate Immune System Pathway (106387); Metabolism Pathway (477135); Metabolism Of Nucleotides Pathway (106263); Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways (366164); Selenium Pathway (219762); Selenium Pathway (198359)
NCBI总结 :
The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt数据库总结 :
TXN: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. Homodimer; disulfide-linked. Interacts with TXNIP through the redox-active site. Interacts with MAP3K5 and CASP3. In case of infection, interacts with S.typhimurium protein slrP. Interacts with APEX1; the interaction stimulates the FOS/JUN AP-1 DNA- binding activity in a redox-dependent manner. Up-regulated by ionizing radiation. Belongs to the thioredoxin family. Protein type: Nuclear receptor co-regulator. Chromosomal Location of Human Ortholog: 9q31. Cellular Component: nucleoplasm; mitochondrion; cytoplasm; nucleus; cytosol. Molecular Function: protein binding; protein disulfide oxidoreductase activity; peptide disulfide oxidoreductase activity. Biological Process: negative regulation of protein export from nucleus; transcription, DNA-dependent; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside and nucleotide interconversion; activation of protein kinase B; negative regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of peptidyl-serine phosphorylation; glycerol ether metabolic process; positive regulation of protein kinase B signaling cascade; cell proliferation; response to reactive oxygen species; response to radiation; cell-cell signaling; cell redox homeostasis; regulation of protein import into nucleus, translocation; innate immune response; cell motility; positive regulation of DNA binding
尺寸1 :
0.5毫克(大肠杆菌)
价格1 :
835美元
尺寸2 :
0.05毫克(杆状病毒)
价格2 :
835
size3 :
0.5毫克(酵母)
价格3 :
1060
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1060
size5 :
1毫克(大肠杆菌)
price5 :
1200
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/977.gif)
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。