蛋白

Recombinant Rat Myosin-binding protein C, cardiac-type

MBS956389

0.05毫克(大肠杆菌)

180美元

重组蛋白

Recombinant Rat Myosin-binding protein C, cardiac-type

肌球蛋白结合蛋白C

C-protein, cardiac muscle isoform

myosin-binding protein C, cardiac-type; Myosin-binding protein C, cardiac-type; myosin-binding protein C, cardiac-type; myosin binding protein C, cardiac; C-protein, cardiac muscle isoform

Mybpc3

Mybpc3; Mybpc3; Cardiac MyBP-C

MYPC_RAT

E Coli or Yeast or Baculovirus or Mammalian Cell

645-864; Provide the fragment include a Ig-like C2-type domain and a Fibronectin type-III domain

864

PKIHLDCPGSTPDTIVVVAGNKLRLDVPISGDPAPTVIW
QKTITQGKKASAGPPPGAPEDAGADEEWVFDKKLLCETE
GRVRVETTKDRSVFTVEGAEKEDEGVYTVTVKNPVGEDQ
VNLTVKVIDVPDAPAAPKISNVGEDSCIVQWEPPAYDGG
QPVLGYILERKKKKSYRWMRLNFDLLRELSHEARRMIEG
VAYEMRVYAVNAVGMSRPSPASQPF

Greater than 90% as determined by SDS-PAGE.

Liquid containing glycerol; lyophilization may be available upon request.

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.

Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.Cardiac myosin-binding protein C (MyBP-C) identification of protein kinase A and protein kinase C phosphorylation sites.Mohamed A.S., Dignam J.D., Schlender K.K.Arch. Biochem. Biophys. 358:313-319(1998)

157824043

NP_001099960.1

NM_001106490.1

P56741

26.1kD

Dilated Cardiomyopathy Pathway (121476); Dilated Cardiomyopathy Pathway (121285); Hypertrophic Cardiomyopathy (HCM) Pathway (114014); Hypertrophic Cardiomyopathy (HCM) Pathway (106591); Muscle Contraction Pathway (1333549); Striated Muscle Contraction Pathway (1333550); Striated Muscle Contraction Pathway (198436)

MYBPC3: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Belongs to the immunoglobulin superfamily. MyBP family. Protein type: Myosin-binding. Cellular Component: A band; myofibril; sarcomere; striated muscle thick filament. Molecular Function: actin binding; identical protein binding; metal ion binding; myosin binding; myosin heavy chain binding; structural constituent of muscle. Biological Process: cardiac muscle contraction; cell adhesion; heart morphogenesis; muscle contraction; myosin filament assembly; regulation of heart contraction; regulation of heart rate; regulation of striated muscle contraction; sarcomere organization; ventricular cardiac muscle morphogenesis

0.05毫克(大肠杆菌)

180美元

0.05毫克(酵母)

260

0.2毫克(大肠杆菌)

490

0.2毫克(酵母)

600

0.5毫克(大肠杆菌)

715