产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
Human Actin, cytoplasmic 2, ACTG1 ELISA Kit
目录 :
MBS944021
规格 :
48-Strip-Wells
价格 :
510美元
更多信息或购买 :
产品信息
目录号 :
MBS944021
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
Human Actin, cytoplasmic 2, ACTG1 ELISA Kit
产品简称 :
肌动蛋白, 丙1
产品名称同义词 :
Human Actin; cytoplasmic 2 (ACTG1) ELISA kit; ACT; ACTG; DFNA20; DFNA26; actin; cytoplasmic 2; actin; gamma 1 propeptide; cytoskeletal gamma-actin; actin; gamma 1
其他名称 :
actin, cytoplasmic 2; Actin, cytoplasmic 2; actin, cytoplasmic 2; cytoskeletal gamma-actin; epididymis luminal protein 176; actin, gamma 1; Gamma-actinCleaved into the following chain:Actin, cytoplasmic 2, N-terminally processed
产品基因名称 :
ACTG1
其他基因名称 :
ACTG1;ACTG1;ACT;ACTG;BRWS2;DFNA20;DFNA26;HEL-176;ACTB;ACTG
UniProt数据库进入名 :
ACTG_HUMAN
反应物种 :
人类
序列长度 :
375
特异性 :
This assay has high sensitivity and excellent specificity for detection of Human ACTG1. No significant cross-reactivity or interference between Human ACTG1 and analogues was observed.
储存稳定性 :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
其它信息1 :
Samples: Serum, plasma, tissue homogenates, Cell lysates. Assay Type: Sandwich. Detection Range: 25 pg/ml-1600 pg/ml. Sensitivity: 6.25 pg/ml
其他信息2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
产品描述 :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ACTG1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ACTG1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ACTG1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ACTG1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI GI登录号 :
316659409
NCBI登录号 :
NP_001186883.1
NCBI基因登录号 :
NM_001199954.1
UniProt数据库登录号 :
P63261
NCBI分子量 :
41,793 Da
NCBI信号通路 :
Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (117293); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (116129); Bacterial Invasion Of Epithelial Cells Pathway (149807); Bacterial Invasion Of Epithelial Cells Pathway (148661); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067)
NCBI总结 :
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
UniProt数据库总结 :
ACTG1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 17q25. Cellular Component: filamentous actin; extracellular space; cytoskeleton; myofibril; membrane; plasma membrane; cytosol; nucleus. Molecular Function: identical protein binding; protein binding; structural constituent of cytoskeleton; ubiquitin protein ligase binding; ATP binding. Biological Process: intercellular junction assembly and maintenance; retinal homeostasis; axon guidance; ephrin receptor signaling pathway; innate immune response; sarcomere organization; vascular endothelial growth factor receptor signaling pathway; cell motility. Disease: Baraitser-winter Syndrome 2; Deafness, Autosomal Dominant 20
尺寸1 :
48-Strip-Wells
价格1 :
510美元
尺寸2 :
96-Strip-Wells
价格2 :
725
size3 :
5x96-Strip-Wells
价格3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
更多信息或购买 :
公司信息
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MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。