产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
PGE synthase Polyclonal Antibody
目录 :
MBS9413039
规格 :
0.05毫升
价格 :
200美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
MyBioSource 产品网页
图像
图像 1 :
MyBioSource MBS9413039 图像 1
Western Blot analysis of A549 cells using PGE synthase Polyclonal Antibody
产品信息
目录号 :
MBS9413039
产品类型 :
抗体
产品全称 :
PGE synthase Polyclonal Antibody
产品简称 :
[PGE synthase]
产品名称同义词 :
[PTGES; MGST1L1; MPGES1; PGES; PIG12; Prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; MGST1-L1; Microsomal prostaglandin E synthase 1; MPGES-1; p53-induced gene 12 protein]
其他名称 :
[prostaglandin E synthase; Prostaglandin E synthase; prostaglandin E synthase; prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; MGST1-L1; Microsomal prostaglandin E synthase 1; MPGES-1; p53-induced gene 12 protein]
产品基因名称 :
[PGE]
其他基因名称 :
[PTGES;PTGES;PGES;MPGES;PIG12;PP102;PP1294;MGST-IV;MGST1L1;TP53I12;mPGES-1;MGST1-L1;MGST1L1;MPGES1;PGES;PIG12;MGST1-L1;MPGES-1]
UniProt数据库进入名 :
PTGES_HUMAN
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
152
特异性 :
PGE synthase Polyclonal Antibody detects endogenous levels of PGE synthase protein.
纯度 :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
形式 :
液体PBS含50% 甘油, 0.5% BSA和0.02% 叠氮化钠
浓度 :
1毫克/毫升
储存稳定性 :
Store at -20 degree C/1 year
检测过的应用 :
免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA)
应用笔记 :
Western Blot: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen Type: peptide. Immunogen Description: Synthesized peptide derived from the Internal region of human PGE synthase.
其他信息2 :
Target Name: PGE synthase
产品种类 :
总数蛋白Ab
NCBI GI登录号 :
4758910
NCBI登录号 :
NP_004869.1
NCBI基因登录号 :
NM_004878.4
UniProt数据库登录号 :
O14684
NCBI分子量 :
17kd
NCBI信号通路 :
Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (1270087); Arachidonic Acid Metabolism Pathway (366); Eicosanoid Synthesis Pathway (198888); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Synthesis Of Prostaglandins (PG) And Thromboxanes (TX) Pathway (1270088)
NCBI总结 :
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
PTGES: Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Belongs to the MAPEG family. Protein type: EC 5.3.99.3; Nuclear envelope; Isomerase; Membrane protein, multi-pass; Membrane protein, integral; Lipid Metabolism - arachidonic acid. Chromosomal Location of Human Ortholog: 9q34.3. Cellular Component: endoplasmic reticulum membrane; membrane; nuclear envelope lumen; perinuclear region of cytoplasm; integral to membrane. Molecular Function: glutathione binding; prostaglandin-E synthase activity. Biological Process: chronic inflammatory response; response to retinoic acid; cyclooxygenase pathway; response to lipopolysaccharide; prostaglandin biosynthetic process; signal transduction; response to organic cyclic substance; prostaglandin metabolic process; negative regulation of cell proliferation; response to cytokine stimulus; arachidonic acid metabolic process; response to calcium ion; acute inflammatory response
尺寸1 :
0.05毫升
价格1 :
200美元
尺寸2 :
0.1毫升
价格2 :
255
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。