产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
cPLA2(磷酸化Ser505)多克隆抗体
目录 :
MBS9400993
规格 :
0.05毫升
价格 :
200美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 酶免疫法
更多信息或购买 :
图像
图像 1 :
Western blot analysis of VEC using p-cPLA2 (S505) antibody.
产品信息
目录号 :
MBS9400993
产品类型 :
抗体
产品全称 :
cPLA2(磷酸化Ser505)多克隆抗体
产品简称 :
[cPLA2]
产品名称同义词 :
[PLA2G4A; CPLA2; PLA2G4; Cytosolic phospholipase A2; cPLA2; Phospholipase A2 group IVA]
其他名称 :
[cytosolic phospholipase A2 isoform 1; Cytosolic phospholipase A2; cytosolic phospholipase A2; phospholipase A2, group IVA (cytosolic, calcium-dependent); Phospholipase A2 group IVAIncluding the following 2 domains:Phospholipase A2 (EC:3.1.1.4)Alternative name(s):Phosphatidylcholine 2-acylhydrolase]
产品基因名称 :
[cPLA2]
其他基因名称 :
[PLA2G4A;PLA2G4A;cPLA2;PLA2G4;cPLA2甲;CPLA2;PLA2G4;cPLA2]
UniProt数据库进入名 :
PA24A_HUMAN
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
749
特异性 :
Phospho-cPLA2 (S505) Polyclonal Antibody detects endogenous levels of cPLA2 protein only when phosphorylated at S505.
纯度 :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
形式 :
液体PBS含50% 甘油, 0.5% BSA和0.02% 叠氮化钠
浓度 :
1毫克/毫升
储存稳定性 :
Store at -20 degree C/1 year
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF), 酶联免疫吸附测定(EIA)
应用笔记 :
Western blotting: 1:500 - 1:2000. Immunohistochemistry: 1:100 - 1:300. Immunofluorescence: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen Type: peptide. Immunogen Description: Synthesized peptide derived from human cPLA2 around the phosphorylation site of S505.
其他信息2 :
Modification: Phospho. Target Species: Human. Target Name: cPLA2
产品种类 :
Phospho-specific Ab
NCBI GI登录号 :
23943920
NCBI登录号 :
NP_077734.1
NCBI基因登录号 :
NM_024420.2
UniProt数据库登录号 :
P47712
NCBI分子量 :
110kd
NCBI信号通路 :
ADP Signalling Through P2Y Purinoceptor 1 Pathway (1269354); AGE/RAGE Pathway (698754); Acyl Chain Remodeling Of CL Pathway (1270071); Acyl Chain Remodelling Of PC Pathway (1270062); Acyl Chain Remodelling Of PE Pathway (1270058); Acyl Chain Remodelling Of PG Pathway (1270069); Acyl Chain Remodelling Of PI Pathway (1270067); Acyl Chain Remodelling Of PS Pathway (1270065); Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (1270087)
NCBI总结 :
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
UniProt数据库总结 :
Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
尺寸1 :
0.05毫升
价格1 :
200美元
尺寸2 :
0.1毫升
价格2 :
255
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。