产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
SARM抗体
目录 :
MBS9400786
规格 :
0.1毫升
价格 :
320美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
图像
图像 1 :
Western blot analysis of SARM in human kidney tissue lysate with SARM antibody at (A) 1 and (B) 2 ug/ml.
产品信息
目录号 :
MBS9400786
产品类型 :
抗体
产品全称 :
SARM抗体
产品简称 :
[SARM]
产品名称同义词 :
[Sterile alpha and TIR motif containing 1]
其他名称 :
[sterile alpha and TIR motif-containing protein 1; Sterile alpha and TIR motif-containing protein 1; sterile alpha and TIR motif-containing protein 1; sterile alpha and TIR motif containing 1; Sterile alpha and Armadillo repeat protein; Sterile alpha motif domain-containing protein 2; MyD88-5; SAM domain-containing protein 2; Tir-1 homolog]
产品基因名称 :
[SARM]
其他基因名称 :
[SARM1;SARM1;SARM;SAMD2;MyD88-5;KIAA0524;SAMD2;SARM;MyD88-5;SAM区域含蛋白2]
UniProt数据库进入名 :
SARM1_HUMAN
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
724
特异性 :
At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. SARM antibody recognize the longest isoform.
纯度 :
Affinity chromatography purified via peptide column
形式 :
PBS含0.02% 叠氮化钠
储存稳定性 :
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen Type: Peptide. Immunogen Description: 16 amino acid peptide near the amino terminus of human SARM.
其他信息2 :
Target Name: SARM
产品种类 :
总数蛋白Ab
NCBI GI登录号 :
154090976
NCBI登录号 :
NP_055892
NCBI基因登录号 :
NM_015077.3
NCBI信号通路 :
Activated TLR4 Signalling Pathway (1269236); Activation Of IRF3/IRF7 Mediated By TBK1/IKK Epsilon Pathway (1269222); IKK Complex Recruitment Mediated By RIP1 Pathway (1269223); Immune System Pathway (1269170); Innate Immune System Pathway (1269203); MyD88-independent TLR3/TLR4 Cascade Pathway (1269220); TRAF6 Mediated Induction Of TAK1 Complex Pathway (1269225); TRIF-mediated TLR3/TLR4 Signaling Pathway (1269221); Toll Like Receptor 3 (TLR3) Cascade Pathway (1269219); Toll Like Receptor 4 (TLR4) Cascade Pathway (1269234)
UniProt数据库总结 :
SARM1: Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88- dependent pathway or non-TLR signaling. Negative regulator of NF- kappa-B and IRF activation. 2 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 17q11. Cellular Component: microtubule; mitochondrion; axon; cytoplasm; dendrite; extrinsic to mitochondrial outer membrane; synapse; cell junction; cytosol. Biological Process: regulation of apoptosis; regulation of dendrite morphogenesis; MyD88-independent toll-like receptor signaling pathway; response to glucose stimulus; toll-like receptor signaling pathway; innate immune response; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway
尺寸1 :
0.1毫升
价格1 :
320美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。