ELISA/assay

小鼠胃泌素释放肽受体(GRPR)酶联免疫吸附试剂盒

MBS9364059

48-Strip-Wells

470美元

酶联免疫吸附试剂盒

小鼠胃泌素释放肽受体(GRPR)酶联免疫吸附试剂盒

[胃泌素释放肽受体(GRPR)]

[gastrin-releasing peptide receptor; Gastrin-releasing peptide receptor; gastrin-releasing peptide receptor; gastrin releasing peptide receptor; GRP-preferring bombesin receptor]

[GRPR]

[GRPR;GRPR;BB2;GRP-R]

GRPR_HUMAN

小鼠

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Chicken Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 31.2ug/ml-1000ug/ml. Sensitivity: 5.0ug/ml.

Intra-assay Precision: Intra-assay CV (%)is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of GRP78 (hereafter termed "analyte") in undiluted original Chicken body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

4885361

NP_005305.1

NM_005314.2

43,199 Da

Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); G Alpha (q) Signalling Events Pathway (1269578); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); GPCRs, Other Pathway (198765); Gastrin-CREB Signalling Pathway Via PKC And MAPK (1269592); Neuroactive Ligand-receptor Interaction Pathway (83053)

Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]

GRPR: Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1. Chromosomal Location of Human Ortholog: Xp22.2. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: peptide receptor activity, G-protein coupled. Biological Process: cell proliferation; G-protein coupled receptor protein signaling pathway; regulation of cell proliferation

48-Strip-Wells

470美元

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095