ELISA/assay

人类丝裂原活化蛋白激酶激酶激酶 12, MAP3K12酶联免疫吸附试剂盒

MBS9326823

48-Strip-Wells

470美元

酶联免疫吸附试剂盒

人类丝裂原活化蛋白激酶激酶激酶 12, MAP3K12酶联免疫吸附试剂盒

[丝裂原活化蛋白激酶激酶激酶 12]

[Human Mitogen-activated protein kinase kinase kinase 12 (MAP3K12) ELISA kit; DLK; MEKK12; MUK; ZPK; ZPKP1; dual leucine zipper kinase DLK; leucine zipper protein kinase; protein kinase MUK; zipper protein kinase; mitogen-activated protein kinase kinase kinase 12]

[mitogen-activated protein kinase kinase kinase 12 isoform 1; Mitogen-activated protein kinase kinase kinase 12; mitogen-activated protein kinase kinase kinase 12; protein kinase MUK; MAPK-upstream kinase; mixed lineage kinase; leucine zipper protein kinase; dual leucine zipper kinase DLK; dual leucine zipper bearing kinase; mitogen-activated protein kinase kinase kinase 12; Dual leucine zipper bearing kinase; DLK; Leucine-zipper protein kinase; ZPK; MAPK-upstream kinase; MUK; Mixed lineage kinase]

[MAP3K12]

[MAP3K12;MAP3K12;DLK;MUK;ZPK;ZPKP1;MEKK12;ZPK;DLK;ZPK;MUK]

M3K12_HUMAN

人类

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MAP3K12 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

301898343

NP_001180440.1

NM_001193511.1

Q12852

96,322 Da

Insulin Signaling Pathway (198845); MAPK Cascade Pathway (198834); MAPK Signaling Pathway (198779); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Regulation Of P38-alpha And P38-beta Pathway (137964)

This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq, Jul 2010]

DLK: May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Protein type: Protein kinase, TKL; Kinase, protein; EC 2.7.11.25; Protein kinase, Ser/Thr (non-receptor); TKL group; MLK family; LZK subfamily. Chromosomal Location of Human Ortholog: 12q13. Cellular Component: growth cone; membrane; axon; cytoplasm; plasma membrane; cytosol. Molecular Function: protein serine/threonine kinase activity; protein binding; protein homodimerization activity; MAP kinase kinase kinase activity; protein kinase binding; ATP binding; protein kinase activity. Biological Process: peptidyl-serine phosphorylation; activation of MAPKK activity; histone phosphorylation; protein amino acid autophosphorylation; peptidyl-threonine phosphorylation; JNK cascade; protein amino acid phosphorylation

48-Strip-Wells

470美元

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095