抗体

QARS多克隆抗体

MBS9127297

0.05毫升

230美元

多克隆

兔

未共轭

免疫印迹, 免疫组化, 免疫细胞化学

抗体

QARS多克隆抗体

QARS

GLNRS;MSCCA;PRO2195

Glutamine--tRNA ligase; Glutamine--tRNA ligase; glutamine--tRNA ligase; glutamine-tRNA synthetase; glutaminyl-tRNA synthetase; Glutaminyl-tRNA synthetase; GlnRS

QARS

QARS;QARS;GLNRS;MSCCA;PRO2195;GlnRS

SYQ_HUMAN

多克隆

IgG

兔

人类, 小鼠

775

亲和纯化

1毫克/毫升

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF)

WB: 1:500 - 1:2000。 IHC: 1:50 - 1:200。 IF: 1:50 - 1:100

Species: Human. Immunogen: Recombinant Protein. Gene ID: 5859

Immunogen: Recombinant protein of human QARS. Calculated Molecular Weight: Refer to figures.

多克隆

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants.

1351170

P47897.1

P47897

775

Aminoacyl-tRNA Biosynthesis Pathway (83030); Aminoacyl-tRNA Biosynthesis Pathway (424); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (413439); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (468360); Cytosolic TRNA Aminoacylation Pathway (105981); Gene Expression Pathway (105937); Metabolic Pathways (132956); Mitochondrial TRNA Aminoacylation Pathway (105982); TRNA Aminoacylation Pathway (105980)

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

QARS: catalyzes the formation of L-glutaminyl-tRNA. Belongs to the class-I aminoacyl-tRNA synthetase family. Protein type: Ligase; EC 6.1.1.18; Mitochondrial; Translation. Chromosomal Location of Human Ortholog: 3p21.31. Cellular Component: mitochondrial matrix; cytoplasm; cytosol. Molecular Function: protein binding; glutamine-tRNA ligase activity; ATP binding. Biological Process: tRNA aminoacylation for protein translation; glutaminyl-tRNA aminoacylation; gene expression; brain development. Disease: Microcephaly, Progressive, With Seizures And Cerebral And Cerebellar Atrophy

0.05毫升

230美元

0.1毫升

305

0.2毫升

460