产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
HBEGF多克隆抗体
目录 :
MBS9126009
规格 :
0.05毫升
价格 :
200美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹
更多信息或购买 :
MyBioSource 产品网页
图像
图像 1 :
MyBioSource MBS9126009 图像 1
Western blot analysis of extracts of various cell lines, using HBEGF antibody (MBS9126009) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
产品信息
目录号 :
MBS9126009
产品类型 :
抗体
产品全称 :
HBEGF多克隆抗体
产品简称 :
[HBEGF]
产品名称同义词 :
[DTR; DTS; DTSF; HEGFL; heparin binding EGF like growth factor.]
其他名称 :
[Proheparin-binding EGF-like growth factor; Proheparin-binding EGF-like growth factor; proheparin-binding EGF-like growth factor; heparin-binding epidermal growth factor; diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); heparin-binding EGF-like growth factor; Diphtheria toxin receptor; DT-R]
产品基因名称 :
[HBEGF]
其他基因名称 :
[HBEGF;HBEGF;DTR;DTS;DTSF;HEGFL;DTR;DTS;HEGFL;HB-EGF;HBEGF;DT-R]
UniProt数据库进入名 :
HBEGF_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
208
纯度 :
亲和纯化
形式 :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
储存稳定性 :
存放在-20°C。 避免反复冷冻/解冻
检测过的应用 :
免疫印迹(免疫印迹)
应用笔记 :
WB: 1:500 - 1:2000
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human HBEGF (NP_001936.1)
产品种类 :
多克隆
NCBI GI登录号 :
544477
NCBI登录号 :
Q99075.1
UniProt数据库登录号 :
Q99075
NCBI分子量 :
Calculated MW: 23kDa. Observed MW: 25kDa
NCBI信号通路 :
Adaptive Immune System Pathway (366160); Constitutive PI3K/AKT Signaling In Cancer Pathway (685535); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550); Disease Pathway (530764); Downstream Signal Transduction Pathway (106385); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (576250); Downstream Signaling Of Activated FGFR Pathway (160957); EGFR Transactivation By Gastrin Pathway (645296); Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway (83102)
UniProt数据库总结 :
HBEGF: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. Protein type: Cell surface; Membrane protein, integral. Chromosomal Location of Human Ortholog: 5q23. Cellular Component: extracellular space; cell surface; integral to plasma membrane; extracellular region; plasma membrane. Molecular Function: heparin binding; growth factor activity; epidermal growth factor receptor binding. Biological Process: epidermal growth factor receptor signaling pathway; positive regulation of keratinocyte migration; muscle development; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; positive regulation of smooth muscle cell proliferation; negative regulation of elastin biosynthetic process; pathogenesis; signal transduction; positive regulation of cell growth; regulation of heart contraction; positive regulation of protein kinase B signaling cascade; positive regulation of cell proliferation; innate immune response; positive regulation of cell migration; wound healing, spreading of epidermal cells
尺寸1 :
0.05毫升
价格1 :
200美元
尺寸2 :
0.1毫升
价格2 :
275
size3 :
0.2毫升
价格3 :
430
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。