WASF2抗体 | MyBioSource MBS854732 产品信息

产品简要

公司名称 :

MyBioSource

产品类型 :

其他

产品名称 :

WASF2抗体

MBS854732

规格 :

0.1毫克

价格 :

280美元

更多信息或购买 :

MyBioSource 产品网页

图像

图像 1 :

Peptide-+

图像 2 :

Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using WASF2antibody. Western blot analysis of extracts from 293 cells, using WASF2 antibody.

产品信息

目录号 :

MBS854732

产品类型 :

抗体

产品全称 :

WASF2抗体

产品简称 :

[WASF2]

产品名称同义词 :

[Wiskott-Aldrich syndrome protein family member 2; WASP family protein member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2; WASF2]

其他名称 :

[wiskott-Aldrich syndrome protein family member 2 isoform 2; Wiskott-Aldrich syndrome protein family member 2; wiskott-Aldrich syndrome protein family member 2; WAS protein family member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2]

产品基因名称 :

[WASF2]

其他基因名称 :

[WASF2; WASF2; IMD2; SCAR2; WASF4; WAVE2; dJ393P12.2; WASP family protein member 2]

反应物种 :

人类, 小鼠, 大鼠

序列长度 :

281

特异性 :

WASF2抗体检测内生水平总数WASF2蛋白

纯度 :

Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

形式 :

In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

储存稳定性 :

Store at-20 degree C for 1 year.

检测过的应用 :

免疫印迹(免疫印迹), 免疫组化(免疫组化), 酶联免疫吸附测定(EIA)

应用笔记 :

WB: 1:500~1:1000。 IHC: 1:50~1:100。 ELISA: 1:1000

image1头 :

试验数据

image2头 :

免疫组化(免疫组化)

其它信息1 :

Immunogen: The antiserum was produced against synthesized peptide derived from internal of human WASF2.

产品种类 :

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

产品引用 :

Suetsugu S., Biochem. Biophys. Res. Commun. 260:296-302(1999). Gregory S.G., Nature 441:315-321(2006). Miki H., Nature 408:732-735(2000).

NCBI GI登录号 :

319655728

NCBI登录号 :

NP_001188333.1

NCBI基因登录号 :

NM_001201404.2

UniProt数据库登录号 :

Q9Y6W5

NCBI分子量 :

31,979 Da

NCBI信号通路 :

Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Bacterial Invasion Of Epithelial Cells Pathway (149807); Bacterial Invasion Of Epithelial Cells Pathway (148661); E-cadherin Signaling In The Nascent Adherens Junction Pathway (138005); ErbB1 Downstream Signaling Pathway (138057); Fc Gamma R-mediated Phagocytosis Pathway (114228); Fc Gamma R-mediated Phagocytosis Pathway (106590); Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (771577); Immune System Pathway (106386)

NCBI总结 :

This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

UniProt数据库总结 :

Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.

尺寸1 :

0.1毫克

价格1 :

280美元

更多信息或购买 :

MyBioSource 产品网页

公司信息