产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
CO3多克隆抗体
目录 :
MBS8531493
规格 :
0.1毫克
价格 :
280美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS8531493
产品类型 :
抗体
产品全称 :
CO3多克隆抗体
产品简称 :
[CO3]
产品名称同义词 :
[Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein; ASP; C3adesArg; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2; C3; CPAMD1]
其他名称 :
[complement C3 preproprotein; Complement C3; complement C3; complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1]
产品基因名称 :
[CO3]
其他基因名称 :
[C3;C3;ASP;C3a;C3b;AHUS5;ARMD9;CPAMD1;HEL-S-62p;CPAMD1;C3bc;ASP]
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
1663
纯度 :
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
形式 :
液体PBS含50% 甘油, 和0.02% 叠氮化钠
储存稳定性 :
Store at-20 degree C for 1 year.
检测过的应用 :
免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA)
应用笔记 :
WB: 1:500-2000。 ELISA: 1:5000-20000
NCBI GI登录号 :
115298678
NCBI登录号 :
NP_000055.2
NCBI基因登录号 :
NM_000064.3
UniProt数据库登录号 :
P01024
NCBI分子量 :
182
NCBI信号通路 :
Activation Of C3 And C5 Pathway (106412); Adaptive Immune System Pathway (366160); Alternative Complement Activation Pathway (106410); Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Complement Activation, Classical Pathway (198823); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484)
NCBI总结 :
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
UniProt数据库总结 :
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
尺寸1 :
0.1毫克
价格1 :
280美元
更多信息或购买 :
公司信息
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MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。