胱氨酸-天冬氨酸蛋白酶9(切断的Asp353)抗体 | MyBioSource MBS852276 产品信息

产品简要

公司名称 :

MyBioSource

产品类型 :

抗体

产品名称 :

胱氨酸-天冬氨酸蛋白酶9(切断的Asp353)抗体

MBS852276

规格 :

0.1毫克

价格 :

215美元

克隆性 :

多克隆

宿主 :

兔

共轭标签 :

未共轭

应用 :

免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法

更多信息或购买 :

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产品信息

目录号 :

MBS852276

产品类型 :

抗体

产品全称 :

胱氨酸-天冬氨酸蛋白酶9(切断的Asp353)抗体

产品简称 :

胱氨酸-天冬氨酸蛋白酶9

产品名称同义词 :

APAF-3; Apoptotic protease Mch-6; Apoptotic protease activating factor 3; CASP-9; Caspase-9; Caspase-9 precursor; EC 3.4.22.-; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; RNCASP9

其他名称 :

Caspase9S;胱氨酸-天冬氨酸蛋白酶

其他基因名称 :

Casp9

UniProt数据库进入名 :

Q9R0S9_MOUSE

宿主 :

兔

反应物种 :

小鼠, 大鼠

序列长度 :

393

特异性 :

Caspase 9 (cleaved-Asp353) antibody detects endogenous levels of fragment of activated Caspase 9 resulting from cleavage adjacent to Asp 353.

纯度 :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

形式 :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

浓度 :

100微克/100微升

储存稳定性 :

Store at -20 degree C for 1 year

检测过的应用 :

免疫印迹(免疫印迹), 免疫组化(免疫组化), 酶联免疫吸附测定(EIA)

应用笔记 :

WB: 1:500~1:1000, IHC: 1:50~1:100, ELISA: 1:20000

其他信息2 :

Immunogen: The antiserum was produced against synthesized peptide derived from mouse Caspase 9. All Sites: Mouse: Asp353; Rat: Asp353. Pathway: Cleaved-specific

产品种类 :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

产品引用 :

Tara Sotsky Kent, Ann. Surg. Oncol., Feb 2004; 11: 192. Yuanming Hu, J. Biol. Chem., Dec 1998; 273: 33489. C.S. Thota, Biol Reprod, Dec 2005; 73: 1191 - 1198. Jonathan H. Lieman, J. Biol. Chem., Mar 2005; 280: 10484 - 10490.

NCBI GI登录号 :

81872787

NCBI登录号 :

Q9R0S9

UniProt数据库登录号 :

Q9R0S9

NCBI分子量 :

42,975 Da

UniProt数据库总结 :

CASP9: a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two isoforms. Protein type: EC 3.4.22.62; Protease; Apoptosis. Cellular Component: mitochondrion; cytoplasm; cytosol; nucleus; apoptosome. Molecular Function: peptidase activity; protein binding; cysteine-type endopeptidase activity; SH3 domain binding; protein kinase binding; cysteine-type peptidase activity. Biological Process: caspase activation; apoptosis; positive regulation of apoptosis; DNA damage response, signal transduction; response to lipopolysaccharide; proteolysis; response to organic cyclic substance; response to estradiol stimulus; response to antibiotic; DNA damage response, signal transduction resulting in induction of apoptosis; positive regulation of neuron apoptosis; response to cobalt ion; response to DNA damage stimulus; response to UV; aging

尺寸1 :

0.1毫克

价格1 :

215美元

更多信息或购买 :

MyBioSource 产品网页

公司信息