产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
PDE3B抗体
目录 :
MBS840862
规格 :
0.2毫克
价格 :
290美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹
更多信息或购买 :
产品信息
目录号 :
MBS840862
产品类型 :
抗体
产品全称 :
PDE3B抗体
产品简称 :
PDE3B
产品名称同义词 :
PDE3B;磷酸二酯酶类型3
其他名称 :
PDE3B protein; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; phosphodiesterase 3B, cGMP-inhibited; CGIPDE1; CGIP1; Cyclic GMP-inhibited phosphodiesterase B; CGI-PDE B
产品基因名称 :
PDE3B
其他基因名称 :
PDE3B;PDE3B;HcGIP1;cGIPDE1;CGIP1;CGI-PDE B
UniProt数据库进入名 :
PDE3B_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
1061
纯度 :
亲和纯化
形式 :
200 ug (0.5 mg/ml) affinity purified rabbit anti-PDE3B polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal. Appearance: Colorless liquid
储存稳定性 :
At -20 degree C for long term storage. Aliquot and freeze at -70 degree C. Avoid repeated freeze/thaw cycles
检测过的应用 :
免疫印迹(免疫印迹)
应用笔记 :
The antibody can be used for Western blotting (1-4 ug/ml). However, the optimal conditions should be determined individually, Blocking peptide (Catalod Number: MBS843957 is available separately.
其它信息1 :
Immunogen: Synthetic peptide surrounding amino acid 948 of mouse PDE3B. Positive Control: Jurkat, Rat kidney, 3T3 cell lysates
其他信息2 :
Handling: The antibody solution should be gently mixed before use.
产品种类 :
Antibodies & Supporting Tools; Primary Antibodies (A-Z)
产品描述 :
Background: The phosphodiesterase type-3 (PDE3) family is comprised of 2 isoforms, PDE3A and PDE3B.Phosphodiesterases (PDE) are crucial in the regulation of the intracellular level of the second messenger cAMP by hydrolyzing cAMP to 5'AMP. PDE3B has two splice variants that are expressed in adipocyte tissue, hepatocyte, kidney, spermatocytes and embryonic neuroepithelium. Both PDE3A and PDE3B are potential targets for the treatment of obesity.
NCBI GI登录号 :
219519624
NCBI登录号 :
AAI44249.1
NCBI分子量 :
118,809 Da
UniProt数据库总结 :
PDE3B: a cGMP-inhibited phosphodiesterase 1 involved in fat metabolism. Inhibition of PDE3B can augment PDE4 inhibitor-induced apoptosis in some patients with chronic lymphocytic leukemia. Protein type: Membrane protein, integral; Nucleotide Metabolism - purine; Membrane protein, multi-pass; EC 3.1.4.17; Phosphodiesterase. Chromosomal Location of Human Ortholog: 11p15.1. Cellular Component: Golgi apparatus; membrane; endoplasmic reticulum; integral to membrane; cytosol. Molecular Function: protein kinase B binding; protein binding; cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; metal ion binding; 3 ,5 -cyclic-nucleotide phosphodiesterase activity. Biological Process: negative regulation of angiogenesis; cellular response to insulin stimulus; negative regulation of lipid catabolic process; cAMP catabolic process; insulin receptor signaling pathway; negative regulation of cell adhesion; angiogenesis; blood coagulation; glucose homeostasis; regulation of insulin secretion; negative regulation of cell adhesion mediated by integrin; endocrine pancreas development
尺寸1 :
0.2毫克
价格1 :
290美元
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/977.gif)
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。