产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
Cardiac Troponin T Rabbit Polyclonal
目录 :
MBS767506
规格 :
0.1毫克
价格 :
290美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 酶免疫法
更多信息或购买 :
图像
图像 1 :
![MyBioSource MBS767506 图像 1](http://www.labome.com/product/MyBioSource/6060201_0.jpg)
Immunohistochemistry of paraffin-embedded human heart using MBS767506 (TNNT2 antibody) at dilution of 1:50.
图像 2 :
![MyBioSource MBS767506 图像 2](http://www.labome.com/product/MyBioSource/6060201_1.jpg)
Mouse heart tissue were subjected to SDS PAGE followed by western blot with MBS767506 ( cTnT Antibody) at dilution of 1:1000.
产品信息
目录号 :
MBS767506
产品类型 :
抗体
产品全称 :
Cardiac Troponin T Rabbit Polyclonal
产品简称 :
[Cardiac Troponin T]
产品名称同义词 :
[Cardiac Troponin T, CMH2, cTnT, TNNT2, TnTC]
其他名称 :
[cardiac troponin T; Troponin T, cardiac muscle; troponin T, cardiac muscle; troponin T2, cardiac type; Cardiac muscle troponin T; cTnT]
其他基因名称 :
[TNNT2; TNNT2; CMH2; RCM3; TnTC; cTnT; CMD1D; CMPD2; LVNC6; TnTc; cTnT]
UniProt数据库进入名 :
TNNT2_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
288
形式 :
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3
储存稳定性 :
Store at -20°C for 24 months (Avoid repeated freeze / thaw cycles.)
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF)
应用笔记 :
Recommended dilution: . WB : 1:500-1:5000. IHC : 1:20-1:200. IF : 1:50-1:500
image1头 :
免疫组化(免疫组化)
image2头 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen: Troponin T type 2 (cardiac). Purification: Immunogen affinity purified. Purity: > 95% as determined by SDS-PAGE
NCBI GI登录号 :
15290516
NCBI登录号 :
AAK92231.1
NCBI分子量 :
34-40 kDa
NCBI信号通路 :
Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Cardiac Progenitor Differentiation Pathway (712094); Cardiac Muscle Contraction Pathway (93344); Cardiac Muscle Contraction Pathway (93992); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); Hypertrophic Cardiomyopathy (HCM) Pathway (114229); Hypertrophic Cardiomyopathy (HCM) Pathway (106591); Muscle Contraction Pathway (1269868)
NCBI总结 :
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
TNNT2: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart. Belongs to the troponin T family. 11 isoforms of the human protein are produced by alternative splicing. Protein type: Motor; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 1q32. Cellular Component: cytosol; sarcomere; striated muscle thin filament; troponin complex. Molecular Function: actin binding; ATPase activity; protein binding; protein binding, bridging; tropomyosin binding; troponin C binding; troponin I binding. Biological Process: actin crosslink formation; cardiac muscle contraction; muscle filament sliding; negative regulation of ATPase activity; positive regulation of ATPase activity; protein heterooligomerization; regulation of heart contraction; regulation of muscle filament sliding speed; response to calcium ion; ventricular cardiac muscle morphogenesis. Disease: Cardiomyopathy, Dilated, 1d; Cardiomyopathy, Familial Hypertrophic, 2; Cardiomyopathy, Familial Restrictive, 3
尺寸1 :
0.1毫克
价格1 :
290美元
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/977.gif)
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。