产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
人类vi型胶原, COLVI酶联免疫吸附试剂盒
目录 :
MBS706172
规格 :
48-Strip-Wells
价格 :
510美元
更多信息或购买 :
产品信息
目录号 :
MBS706172
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
人类vi型胶原, COLVI酶联免疫吸附试剂盒
产品简称 :
胶原, 类型VI, 甲1
产品名称同义词 :
Human Collagen Type VI (COLVI) ELISA Kit; OPLL; alpha 1 (VI) chain (61 AA) ; collagen VI; alpha-1 polypeptide; collagen; type VI; alpha 1
其他名称 :
collagen alpha-1(VI) chain; Collagen alpha-1(VI) chain; collagen alpha-1(VI) chain; collagen alpha-1(VI) chain; alpha 1 (VI) chain (61 AA); collagen VI, alpha-1 polypeptide; collagen, type VI, alpha 1
产品基因名称 :
COL6A1
其他基因名称 :
COL6A1;COL6A1;OPLL
UniProt数据库进入名 :
CO6A1_HUMAN
反应物种 :
人类
序列长度 :
1028
特异性 :
This assay has high sensitivity and excellent specificity for detection of human COLVI. No significant cross-reactivity or interference between human COLVI and analogues was observed.
储存稳定性 :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
其它信息1 :
Samples: Serum, plasma, cell culture supernates, urine. Assay Type: Sandwich. Detection Range: 31.25 pg/ml -2000 pg/ml. Sensitivity: The minimum detectable dose of human COLVI is typically less than 7.81 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
其他信息2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
产品描述 :
Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for COLVI has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any COLVI present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for COLVI is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of COLVI bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI GI登录号 :
87196339
NCBI登录号 :
NP_001839.2
NCBI基因登录号 :
NM_001848.2
UniProt数据库登录号 :
P12109
NCBI分子量 :
108,529 Da
NCBI信号通路 :
Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (730306); Axon Guidance Pathway (105688); Collagen Biosynthesis And Modifying Enzymes Pathway (645289); Collagen Formation Pathway (645288); Developmental Biology Pathway (477129); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Extracellular Matrix Organization Pathway (576262); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478)
NCBI总结 :
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Function: Collagen VI acts as a cell-binding protein.
尺寸1 :
48-Strip-Wells
价格1 :
510美元
尺寸2 :
96-Strip-Wells
价格2 :
725
size3 :
5x96-Strip-Wells
价格3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
更多信息或购买 :
公司信息
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MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。