产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
人类白细胞介素23亚单位甲, IL-23A酶联免疫吸附试剂盒
目录 :
MBS706156
规格 :
48-Strip-Wells
价格 :
565美元
更多信息或购买 :
产品信息
目录号 :
MBS706156
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
人类白细胞介素23亚单位甲, IL-23A酶联免疫吸附试剂盒
产品简称 :
白细胞介素23, 甲亚单位p19
产品名称同义词 :
Human Interleukin-23 subunit alpha (IL-23A) Elisa kit; IL-23; IL-23A; IL23P19; MGC79388; P19; SGRF; JKA3 induced upon T-cell activation; interleukin 23 p19 subunit; interleukin 23; alpha subunit p19
其他名称 :
interleukin-23 subunit alpha; Interleukin-23 subunit alpha; interleukin-23 subunit alpha; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin 23 p19 subunit; interleukin-23 subunit p19; JKA3 induced upon T-cell activation; interleukin-six, G-CSF related factor; interleukin 23, alpha subunit p19; Interleukin-23 subunit p19; IL-23p19
产品基因名称 :
IL23A
其他基因名称 :
IL23A;IL23A;P19;SGRF;IL-23;IL-23A;IL23P19;SGRF;UNQ2498/PRO5798;IL-23亚单位甲;IL-23;IL-23p19
UniProt数据库进入名 :
IL23A_HUMAN
反应物种 :
人类
序列长度 :
189
特异性 :
This assay has high sensitivity and excellent specificity for detection of Human IL23A. No significant cross-reactivity or interference between Human IL23A and analogues was observed.
储存稳定性 :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
其它信息1 :
Samples: Serum, plasma, cell culture supernates, tissue homogenates and Cell lysates. Assay Type: Sandwich. Detection Range: 62.5 pg/ml-4000 pg/ml. Sensitivity: 15.6 pg/ml
其他信息2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Immunity. Protein Biological Process 3: Antiviral defense
产品描述 :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL-23A has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL-23A present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL-23A is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL-23A bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI GI登录号 :
7706702
NCBI登录号 :
NP_057668.1
NCBI基因登录号 :
NM_016584.2
UniProt数据库登录号 :
Q9NPF7
NCBI分子量 :
20,730 Da
NCBI信号通路 :
ATF-2 Transcription Factor Network Pathway (138006); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL23-mediated Signaling Events Pathway (138000); Inflammatory Bowel Disease (IBD) Pathway (842771); Inflammatory Bowel Disease (IBD) Pathway (842797); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Pertussis Pathway (218111); Pertussis Pathway (218099)
NCBI总结 :
This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Function: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.3 PublicationsManual assertion based on experiment in:Ref.1
尺寸1 :
48-Strip-Wells
价格1 :
565美元
尺寸2 :
96-Strip-Wells
价格2 :
810
size3 :
5x96-Strip-Wells
价格3 :
2750
size4 :
10x96-Strip-Wells
price4 :
5150
更多信息或购买 :
公司信息
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MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。
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