ELISA/assay

小鼠血小板衍生生长因子CC, PDGF-CC酶联免疫吸附试剂盒

MBS705088

48-Strip-Wells

565美元

酶联免疫吸附试剂盒

小鼠血小板衍生生长因子CC, PDGF-CC酶联免疫吸附试剂盒

血小板衍生生长因子C

Mouse platelet-derived growth factor CC (PDGF-CC) ELISA Kit; FALLOTEIN; SCDGF; platelet-derived growth factor C; secretory growth factor-like protein; spinal cord-derived growth factor; platelet derived growth factor C

platelet-derived growth factor C; Platelet-derived growth factor C; platelet-derived growth factor C; SCDGF; VEGF-E; fallotein; spinal cord-derived growth factor; platelet-derived growth factor, C polypeptide; Fallotein; Spinal cord-derived growth factor; SCDGF; VEGF-ECleaved into the following 2 chains:Platelet-derived growth factor C, latent form; PDGFC latent form; Platelet-derived growth factor C, receptor-binding form; PDGFC receptor-binding form

PDGFC

Pdgfc; Pdgfc; PDGF-C; AI647969; 1110064L01Rik; Scdgf; PDGF-C; SCDGF; PDGFC latent form; PDGFC receptor-binding form

PDGFC_MOUSE

小鼠

345

This assay has high sensitivity and excellent specificity for detection of mouse PDGF-CC. No significant cross-reactivity or interference between mouse PDGF-CC and analogues was observed.

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Samples: Serum, plasma, cell culture supernates, tissue homogenates,. Assay Type: Sandwich. Detection Range: 62.5 pg/ml-4000 pg/ml. Sensitivity: Typically less than 15.6 pg/ml

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PDGF-CC has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PDGF-CC present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PDGF-CC is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PDGF-CC bound in the initial step. The color development is stopped and the intensity of the color is measured.

10242385

NP_064355.1

NM_019971.2

Q8CI19

38,741 Da

Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Focal Adhesion Pathway (198353); Focal Adhesion Pathway (83264); Focal Adhesion Pathway (478); Gap Junction Pathway (83269); Gap Junction Pathway (483); Melanoma Pathway (83307); Melanoma Pathway (526); PI3K-Akt Signaling Pathway (692242)

Function: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.8 PublicationsManual assertion based on experiment in:Ref.6

48-Strip-Wells

565美元

96-Strip-Wells

810

5x96-Strip-Wells

2750

10x96-Strip-Wells

5150