产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
小鼠抗人类CD200
目录 :
MBS690039
规格 :
0.1毫克
价格 :
475美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
(2K50)
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
MBS690039
产品类型 :
抗体
产品全称 :
小鼠抗人类CD200
产品简称 :
CD200
产品名称同义词 :
CD200;MRC;MOX1;MOX2;OX-2
其他名称 :
OX-2 membrane glycoprotein isoform b; OX-2 membrane glycoprotein; OX-2 membrane glycoprotein; CD200 antigen; MRC OX-2 antigen; antigen identified by monoclonal antibody MRC OX-2; CD200 molecule
产品基因名称 :
CD200
其他基因名称 :
CD200;CD200;MRC;MOX1;MOX2;OX-2;MOX1;MOX2
UniProt数据库进入名 :
OX2G_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG1
克隆 :
(2K50)
宿主 :
小鼠
反应物种 :
人类
序列长度 :
294
纯度 :
蛋白质G色谱
形式 :
冻干
储存稳定性 :
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.
检测过的应用 :
Neutr
其它信息1 :
Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CD200.
其他信息2 :
Reconstitution: Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.
产品描述 :
CD200 antigen, also known as OX-2, is a type I transmembrane protein belonging to the Ig superfamily. It has a 202 amino acid extracellular domain and a short (19 aa) cytoplasmic tail. At least two alternate splice isoforms exist that differ in their cytoplasmic domains. CD200 is widely expressed in multiple cell types. It interacts with CD200 R1, another Ig superfamily inhibitory receptor primarily expressed on leukocytes of the myeloid lineage, to inhibit myeloid functions.
NCBI GI登录号 :
90903245
NCBI登录号 :
NP_001004196.2
NCBI基因登录号 :
NM_001004196.2
UniProt数据库登录号 :
P41217
NCBI分子量 :
31,264 Da
NCBI信号通路 :
Adaptive Immune System Pathway (366160); Immune System Pathway (106386); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (106413)
NCBI总结 :
The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Function: Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. Subunit structure: Interacts with CD200R1. Subcellular location: Cell membrane; Single-pass type I membrane protein. Sequence similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain.
尺寸1 :
0.1毫克
价格1 :
475美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。