蛋白

白细胞介素6, 重组, 大鼠(IL-6)

MBS650023

0.002毫克

275美元

重组蛋白

白细胞介素6, 重组, 大鼠(IL-6)

白细胞介素6, 大鼠

白细胞介素6;白细胞介素6;白细胞介素6;IL-6;白细胞介素6(干扰素, 乙2);白细胞介素6

白细胞介素-6;白细胞介素-6;ILg6;Ifnb2;白细胞介素6

IL6_RAT

MFPTSQVRRG DFTEDTTHNR PVYTTSQVGG LITYVLREIF EMRKELCNGN SDCMNSDDAL SENNLKLPEI QRNDGCFQTG YNQEICLLKI CSGLLEFRFY LEFVKNNLQD NKKDKARVIQ SNTETLVHIF KQEIKDSYKI VLPTPTSNAL LMEKLESQKE WLRTKTIQLI LKALEEFLKV TMRSTRQT

Highly Purified. ~95% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug)

Supplied as a lyophilized powder. Reconstitute with dH2O, 0.1% HSA or BSA to 0.1-1mg/ml. Further dilutions can be made into other buffered solutions.

Lyophilized powder may be stored dessicated at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile dH2O, 0.1% HSA or BSA. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer

Biological Activity: Rat IL-6 is fully biologically active when compared to standards. The ED50 was determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is. 1x10e8 units/mg.

生长因子, 细胞因子;生长因子白细胞介素

Interleukin-6 (IL-6) is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. Rat IL-6 is a 21.7kD protein containing 187 amino acid residues.

7549769

NP_036721.1

NM_012589.1

P20607

21.7kD

Adipogenesis Pathway (198479); African Trypanosomiasis Pathway (194377); African Trypanosomiasis Pathway (194323); Amoebiasis Pathway (167311); Amoebiasis Pathway (167191); Androgen Receptor Signaling Pathway (198529); Chagas Disease (American Trypanosomiasis) Pathway (147806); Chagas Disease (American Trypanosomiasis) Pathway (147795); Cytokine-cytokine Receptor Interaction Pathway (83443); Cytokine-cytokine Receptor Interaction Pathway (460)

a cytokine involved in development and possibly in neurodegenerative processes [RGD]

Function: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. Subcellular location: Secreted. Sequence similarities: Belongs to the IL-6 superfamily.

0.002毫克

275美元

0.01毫克

340