蛋白

小鼠CD200重组(MOX1)

MBS553287

0.02毫克

220美元

重组蛋白

小鼠CD200重组(MOX1)

[CD200(MOX1)]

[小鼠CD200重组(MOX1);CD200;MOX1;MOX2;MRC;OX-2]

[OX-2膜糖蛋白;OX-2膜糖蛋白;MRC OX-2抗原]

[CD200]

[Cd200;Mox2]

OX2G_MOUSE

278

>98%, as determined by SDS-PAGE and HPLC

Recombinant CD200 is supplied as a 0.2 um filtered PBS solution, pH7.2.

Recombinant CD200, as supplied, can be stored in working aliquots at 2°- 8 degree C for one month, or at -20°C to -70°C for twelve months. Avoid repeated freeze/thaw cycles.

Source: Optimized DNA sequence encoding extracellular domain of Mouse CD200 including a C-terminal 6His tag was expressed in HEK293 cells. Molecular Weight: Recombinant Mouse CD200 is a monomer protein consisting of 213 amino acid residue subunits, due to glycosylation migrates as an approximately 40-45kDa protein on SDS-PAGE.

Biological Activity: The activity was tested by the ability of immobilized recombinant mouse CD200 (1ug/ml, 100ul/well) to bind mouse CD200R1 with a linear range of 1-200 ng/ml. Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).

受体Coding sequence蛋白质编码序列

CD200 is preferentially expressed in cd138 dim multiple myeloma cells: implications for a myeloma stem cell subpopulation with potential immune-resistance. . Blood (ASH Annual Meeting Abstracts), Nov 2009; 114: 4877. essential roles for dok2 and rasgap in CD200 receptor-mediated regulation of human myeloid cells . J. Immunol., Oct 2009; 183: 4879 - 4886. lack of CD200 enhances pathological t cell responses during influenza infection . J. Immunol., Aug 2009; 183: 1990 - 1996. expression of a CD200 transgene is necessary for induction but not maintenance of tolerance to cardiac and skin allografts . J. Immunol., Aug 2009; 183: 1560 - 1568. induction of CD200 signalling reduces inflammatory cell infiltration and inhibits laser-induced choroidal neovascularization . Invest. Ophthalmol. Vis. Sci., Apr 2009; 50: 3759.

26006825

O54901.1

O54901

CD200: Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Cellular Component: membrane; integral to membrane; plasma membrane. Molecular Function: protein binding

0.02毫克

220美元

0.1毫克

540

0.5毫克

1915