产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
磷酸甘油醛脱氢酶抗体
目录 :
MBS534081
规格 :
0.1毫升
价格 :
180美元
克隆性 :
多克隆
宿主 :
羊
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS534081
产品类型 :
抗体
产品全称 :
磷酸甘油醛脱氢酶抗体
产品简称 :
磷酸甘油醛脱氢酶
产品名称同义词 :
多克隆磷酸甘油醛脱氢酶;抗磷酸甘油醛脱氢酶;磷酸甘油醛脱氢酶
其他名称 :
glyceraldehyde-3-phosphate dehydrogenase isoform 1; Glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase GAPDH (EC:2.6.99.-)
产品基因名称 :
磷酸甘油醛脱氢酶
其他基因名称 :
磷酸甘油醛脱氢酶;磷酸甘油醛脱氢酶;G3PD;GAPD;HEL-S;GAPD;磷酸甘油醛脱氢酶
UniProt数据库进入名 :
G3P_HUMAN
克隆性 :
多克隆
宿主 :
羊
反应物种 :
人类, 兔, 大肠杆菌
序列长度 :
335
形式 :
Purified IgG fraction supplied in PBS, pH 7.2 with 0.1% NaN3.
储存稳定性 :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles.
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)
其它信息1 :
Biological Significance: Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is an enzyme that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. In addition to this long established metabolic function, GAPDH has recently been implicated in several non-metabolic processes, including transcription activation, initiation of apoptosis, and ER to Golgi vesicle shuttling.
其他信息2 :
Biohazard Information: This product contains sodium azide (NaN3), a chemical highly toxic in pure form. At product concentrations, though not classified as hazardous, NaN3 may react with lead and copper plumbing to form highly explosive build-ups of metal azides. Upon disposal, flush with large volumes of water to prevent metal azide build-up in plumbing. Immunogen: GAPDH antibody was raised in sheep using a 12 amino acid synthetic peptide (HQVVSSDFNSDT) representing the most conserved region of human and rat GAPDH conjugated with KLH as the immunogen.
产品种类 :
Proteases, Inhibitors, & Enzymes
产品描述 :
羊多克隆磷酸甘油醛脱氢酶抗体
产品引用 :
Silica Crystals and Aluminum Salts Regulate the Production of Prostaglandin in Macrophages via NALP3 Inflammasome-Independent Mechanisms; Etsushi Kuroda, Ken J. Ishii, Satoshi Uematsu, Keiichi Ohata, Cevayir Coban, Shizuo Akira, Kosuke Aritake, Yoshihiro Urade, Yasuo Morimoto (Immunity: Volume: 34 Issue: 4 Page: 514-526 DOI: 10.1016/j.immuni.2011.03.019). The reduction of voluntary physical activity after poly I:C injection is independent of the effect of poly I:C-induced interferon-beta in mice; Takashi Matsumotoa, Hiroshi Takahashia, Daisuke Shivab, Noriaki Kawanishia, Michael J. Kremenika, Yasuko Katoc, Hiromi Yano (Physiology & Behavior: Volume: 93 Issue: 4-5 Page: 835-841 DOI: 10.1016/j.physbeh.2007.11.048). Calcineurin protects the heart in a murine model of dilated cardiomyopathy; Joerg Heinekea, b, Kai C. Wollertb, Hanna Osinskaa, Michelle A. Sargenta, Allen J. Yorka, Jeffrey Robbinsa, Jeffery D. Molkentin (Journal of Molecular and Cellular Cardiology: Volume: 48 Issue: 6 Page: 1080-1087 DOI: 10.1016/j.yjmcc.2009.10.012)
NCBI GI登录号 :
7669492
NCBI登录号 :
NP_002037.2
NCBI基因登录号 :
NM_002046.4
UniProt数据库登录号 :
P04406
NCBI分子量 :
31,548 Da
NCBI信号通路 :
Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!Alzheimers Disease Pathway 672448!!Biosynthesis Of Amino Acids Pathway 790012!!Biosynthesis Of Amino Acids Pathway 795174!!Biosynthesis Of Antibiotics Pathway 1144997!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Gluconeogenesis Pathway 106204!!Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway 413342
NCBI总结 :
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
规格 :
0.1毫升
价格 :
180美元
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/977.gif)
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。