ELISA/assay

人类乙酰辅酶A羧化酶2, ACACB酶联免疫吸附试剂盒

MBS2602872

96 Strip Wells

420美元

酶联免疫吸附试剂盒

人类乙酰辅酶A羧化酶2, ACACB酶联免疫吸附试剂盒

acetyl-Coenzyme A carboxylase beta

acetyl-CoA carboxylase 2; Acetyl-CoA carboxylase 2; acetyl-CoA carboxylase 2; ACC-beta; acetyl-Coenzyme A carboxylase beta; acetyl-CoA carboxylase beta; ACC-betaIncluding the following 1 domains:Biotin carboxylase (EC:6.3.4.14)

ACACB;ACACB;ACC2;ACCB;HACC275;ACC2;ACCB

ACACB_HUMAN

人类

Store all reagents at 2-8 degree C.

134142062

NP_001084.3

NM_001093.3

O00763

276,541 Da

AMPK Signaling Pathway 198868!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!ChREBP Activates Metabolic Gene Expression Pathway 106104!!Fatty Acid Biosynthesis Pathway 198873!!Fatty Acid Biosynthesis Pathway 82933!!Fatty Acid Biosynthesis Pathway 294!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway 106108!!Insulin Signaling Pathway 83090

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]

Function: ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Catalytic activity: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.1 PublicationManual assertion based on experiment in:Ref.9. Cofactor: Biotin 1 PublicationManual assertion based on experiment in:Ref.2. Enzyme regulation: Activity is increased by oligomerization. Activated by citrate. Citrate and MID1IP1 promote oligomerization. Inhibited by malonyl-CoA.2 PublicationsManual assertion based on experiment in:Ref.2

96 Strip Wells

420美元