产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
人类乙酰辅酶A羧化酶2, ACACB酶联免疫吸附试剂盒
目录 :
MBS2602872
规格 :
96 Strip Wells
价格 :
420美元
更多信息或购买 :
产品信息
目录号 :
MBS2602872
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
人类乙酰辅酶A羧化酶2, ACACB酶联免疫吸附试剂盒
产品简称 :
acetyl-Coenzyme A carboxylase beta
其他名称 :
acetyl-CoA carboxylase 2; Acetyl-CoA carboxylase 2; acetyl-CoA carboxylase 2; ACC-beta; acetyl-Coenzyme A carboxylase beta; acetyl-CoA carboxylase beta; ACC-betaIncluding the following 1 domains:Biotin carboxylase (EC:6.3.4.14)
其他基因名称 :
ACACB;ACACB;ACC2;ACCB;HACC275;ACC2;ACCB
UniProt数据库进入名 :
ACACB_HUMAN
反应物种 :
人类
储存稳定性 :
Store all reagents at 2-8 degree C.
NCBI GI登录号 :
134142062
NCBI登录号 :
NP_001084.3
NCBI基因登录号 :
NM_001093.3
UniProt数据库登录号 :
O00763
NCBI分子量 :
276,541 Da
NCBI信号通路 :
AMPK Signaling Pathway 198868!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!ChREBP Activates Metabolic Gene Expression Pathway 106104!!Fatty Acid Biosynthesis Pathway 198873!!Fatty Acid Biosynthesis Pathway 82933!!Fatty Acid Biosynthesis Pathway 294!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway 106108!!Insulin Signaling Pathway 83090
NCBI总结 :
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Function: ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Catalytic activity: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.1 PublicationManual assertion based on experiment in:Ref.9. Cofactor: Biotin 1 PublicationManual assertion based on experiment in:Ref.2. Enzyme regulation: Activity is increased by oligomerization. Activated by citrate. Citrate and MID1IP1 promote oligomerization. Inhibited by malonyl-CoA.2 PublicationsManual assertion based on experiment in:Ref.2
规格 :
96 Strip Wells
价格 :
420美元
更多信息或购买 :
公司信息
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MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。
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