产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
大鼠PDGF-C(血小板衍生生长因子C)酶联免疫吸附试剂盒
目录 :
MBS2503234
规格 :
24-Strip-Wells
价格 :
215美元
更多信息或购买 :
图像
图像 1 :
![MyBioSource MBS2503234 图像 1](http://www.labome.com/product/MyBioSource/6056504_0.jpg)
产品信息
目录号 :
MBS2503234
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
大鼠PDGF-C(血小板衍生生长因子C)酶联免疫吸附试剂盒
产品简称 :
[PDGF-C]
其他名称 :
[platelet-derived growth factor C; Platelet-derived growth factor C; platelet-derived growth factor C; PDGF-C; VEGF-E; secretory growth factor-like protein; spinal cord-derived growth factor; platelet derived growth factor C; Fallotein; Spinal cord-derived growth factor; SCDGF; VEGF-ECleaved into the following 2 chains:Platelet-derived growth factor C, latent form; PDGFC latent form; Platelet-derived growth factor C, receptor-binding form; PDGFC receptor-binding form]
产品基因名称 :
[PDGF-C]
其他基因名称 :
[PDGFC; PDGFC; SCDGF; FALLOTEIN; SCDGF; PDGF-C; SCDGF; PDGFC latent form; PDGFC receptor-binding form]
UniProt数据库进入名 :
PDGFC_HUMAN
反应物种 :
大鼠
序列长度 :
345
特异性 :
This assay has high sensitivity and excellent specificity for detection of Rat PDGF-C. No significant cross-reactivity or interference between Rat PDGF-C and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Rat PDGF-C and all the analogues, therefore, cross reaction may still exist.
储存稳定性 :
Store at 4 degree C.
image1头 :
Typical Testing Data/Standard Curve (for reference only)
其它信息1 :
Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 15.625-1000pg/mL. Sensitivity: Min: 9.375pg/mL; Max: 1000pg/mL
产品描述 :
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of PDGF-C in Rat serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat PDGF-C. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Rat PDGF-C and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat PDGF-C, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Rat PDGF-C. You can calculate the concentration of Rat PDGF-C in the samples by comparing the OD of the samples to the standard curve.
NCBI GI登录号 :
9994187
NCBI登录号 :
NP_057289.1
NCBI基因登录号 :
NM_016205.2
UniProt数据库登录号 :
Q9NRA1
NCBI分子量 :
20,609 Da
NCBI信号通路 :
Choline Metabolism In Cancer Pathway (1059539); Choline Metabolism In Cancer Pathway (1084232); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); Gap Junction Pathway (83072); Gap Junction Pathway (483); Melanoma Pathway (83114)
NCBI总结 :
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
UniProt数据库总结 :
PDGFC: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function. Belongs to the PDGF/VEGF growth factor family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 4q32. Cellular Component: Golgi membrane; extracellular space; cell surface; endoplasmic reticulum lumen; cytoplasm; plasma membrane; extracellular region; nucleus. Molecular Function: protein binding; protein homodimerization activity; growth factor activity; platelet-derived growth factor receptor binding. Biological Process: embryonic development; organ morphogenesis; positive regulation of fibroblast proliferation; transmembrane receptor protein tyrosine kinase activation (dimerization); central nervous system development; positive regulation of cell division; platelet-derived growth factor receptor signaling pathway; regulation of peptidyl-tyrosine phosphorylation; positive regulation of DNA replication
尺寸1 :
24-Strip-Wells
价格1 :
215美元
尺寸2 :
48-Strip-Wells
价格2 :
410
size3 :
96-Strip-Wells
价格3 :
490
size4 :
5x96-Strip-Wells
price4 :
2040
size5 :
10x96-Strip-Wells
price5 :
3590
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/977.gif)
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。