产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
HRP-Linked Polyclonal Antibody to Thioredoxin (Trx)
目录 :
MBS2046307
规格 :
0.1毫克
价格 :
255美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
HRP
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
更多信息或购买 :
图像
图像 1 :
![MyBioSource MBS2046307 图像 1](http://www.labome.com/product/MyBioSource/6056296_0.jpg)
产品信息
目录号 :
MBS2046307
产品类型 :
抗体
产品全称 :
HRP-Linked Polyclonal Antibody to Thioredoxin (Trx)
产品简称 :
[Thioredoxin (Trx)]
产品名称同义词 :
[TXN; ADF; SASP; TRDX; TRX1; ATL-derived factor; Surface-associated sulphydryl protein]
其他名称 :
[硫氧还蛋白;硫氧还蛋白;硫氧还蛋白;硫氧还蛋白1]
产品基因名称 :
[Trx]
其他基因名称 :
[Txn1; Txn; Txn; Txn1; Trx]
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类
纯度 :
Antigen-specific Affinity Chromatography
形式 :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
浓度 :
200微克/毫升
储存稳定性 :
Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
检测过的应用 :
免疫印迹;免疫组化;免疫细胞化学
应用笔记 :
Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-20ug/mL. Immunocytochemistry: 5-20ug/mL. Optimal working dilutions must be determined by end user
image1头 :
Wetsern Blot
其它信息1 :
Source: Antibody labeling. Label: HRP. Traits: Liquid. Immunogen: Recombinant Thioredoxin (MET1~Val105) expressed in E.coli.
其他信息2 :
Unconjugated Antibody: The unconjugated antibody version of this item is also available as catalog #MBS2001389
NCBI GI登录号 :
16758644
NCBI登录号 :
NP_446252.1
NCBI基因登录号 :
NM_053800.3
NCBI信号通路 :
Cellular Senescence Pathway (935708); Cellular Responses To Stress Pathway (935701); Detoxification Of Reactive Oxygen Species Pathway (935707); Immune System Pathway (936650); Inflammasomes Pathway (936724); Innate Immune System Pathway (936679); Metabolism Pathway (935443); Metabolism Of Nucleotides Pathway (935606); NFE2L2 Pathway (739005); Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways (936722)
NCBI总结 :
protein-disulfide reductase enzyme that is important for redox signalling during apoptosis and cell growth [RGD, Feb 2006]
UniProt数据库总结 :
TXN: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. Homodimer; disulfide-linked. Interacts with TXNIP through the redox-active site. Interacts with MAP3K5 and CASP3. In case of infection, interacts with S.typhimurium protein slrP. Interacts with APEX1; the interaction stimulates the FOS/JUN AP-1 DNA- binding activity in a redox-dependent manner. Up-regulated by ionizing radiation. Belongs to the thioredoxin family. Protein type: Nuclear receptor co-regulator. Chromosomal Location of Human Ortholog: 5q24. Cellular Component: axon; cell soma; cytoplasm; cytosol; dendrite; mitochondrion; nucleus. Molecular Function: enzyme binding; oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor; peptide disulfide oxidoreductase activity; protein disulfide oxidoreductase activity; protein-disulfide reductase activity; thioredoxin-disulfide reductase activity. Biological Process: cell redox homeostasis; negative regulation of protein export from nucleus; negative regulation of transcription from RNA polymerase II promoter; positive regulation of DNA binding; positive regulation of peptidyl-serine phosphorylation; regulation of protein import into nucleus, translocation; response to activity; response to axon injury; response to drug; response to radiation; response to selenium ion
尺寸1 :
0.1毫克
价格1 :
255美元
尺寸2 :
0.2毫克
价格2 :
395
size3 :
1毫克
价格3 :
935
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/977.gif)
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。
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